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http://dx.doi.org/10.5698/1535-7597.18.1.56 | DOI Listing |
Ecotoxicol Environ Saf
December 2024
Jiangxi Engineering Laboratory of Zebrafish Modeling and Drug Screening for Human Diseases, Jiangxi Key Laboratory of Developmental Biology of Organs and Epigenetics, Key Laboratory of Jiangxi Province for Biological Invasion and Biosecurity, College of Life Sciences, Clinical Research Center of Affiliated Hospital of Jinggangshan University, Jinggangshan University, Ji'an 343009, China. Electronic address:
With the widespread application of pesticides, water pollution problems are becoming more and more serious, which is very likely to cause harm to fish. Lower vertebrates, including fish, have the ability to repair damaged tissues. The spread of pesticides in the water may affect their regeneration process after injury, leading to their death, thereby affecting the survival rate of the population.
View Article and Find Full Text PDFSchizophrenia (Heidelb)
December 2024
Department of Psychiatry, First Hospital of Shanxi Medical University, Taiyuan, China.
Genes discovered by previous epigenetic studies of schizophrenia have focused solely on diagnostics or pathology, potentially leading to a disconnection between them. Using these molecules to identify the disease is considered insufficient. MicroRNAs (miRNAs) binding to messenger RNAs (mRNAs) can lead to mRNA degradation, while circular RNAs (circRNAs), by binding to miRNAs as sponge, can reduce the inhibitory effect of miRNAs on mRNAs.
View Article and Find Full Text PDFTrends Genet
December 2024
Biological Sciences, North Dakota State University, Fargo, ND, USA. Electronic address:
Transposable elements (TEs) shape every aspect of genome biology, influencing genome stability, size, and organismal fitness. Following the 2007 discovery of the piRNA defense system, researchers have made numerous findings about organisms' defenses against these genomic invaders. TEs are suppressed by a 'genomic immune system', where TE insertions within specialized regions called PIWI-interacting RNA (piRNA) clusters produce small RNAs responsible for their suppression.
View Article and Find Full Text PDFBioorg Chem
December 2024
Jiangxi Key Laboratory of Natural Product and Functional Food, College of Food Science and Engneering, Jiangxi Agricultural University, Nanchang 330045, People's Republic of China. Electronic address:
SO is commonly used to ensure the safety of food, but englobing of excessive SO poses serious risks to human health. Additionally, as fourth gaseous signaling molecule, it plays a critical role in various physiological processes. Therefore, monitoring the concentration of SO in food and cells is crucial for correlative research and disease diagnosis.
View Article and Find Full Text PDFPLoS Biol
December 2024
Department of Biology, Washington University in St. Louis, St. Louis, Missouri, United States of America.
In eukaryotes, defective mRNAs that impede the movement of the ribosome are subject to rapid decay via no-go decay (NGD). In this issue of PLOS Biology, Ishibashi and colleagues expand on the role of NGD and reveal new endogenous targets for the process in zebrafish.
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