This study focuses upon 38 patients found to have unsuspected carcinomas or lobular neoplasia in fibroadenomatous tumors. Combining the pathologic and clinical features of these patients with those of 56 comparable instances reported upon in the literature, it becomes apparent that the biologic and clinical behavior of lobular neoplasia, intraductal carcinomas and invasive carcinomas is essentially the same regardless of whether the lesions arise in or outside a fibroadenoma. In addition, they are often a part of a multifocal malignant condition in the ipsilateral or contralateral breast. These patients, therefore, should be treated as if the carcinomas or lobular neoplasia arose in the usual setting.
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