AI Article Synopsis
- The study investigates the toxicity of collagen from gouramy fish scales by testing its effects on baby hamster kidney fibroblasts (BHK-21).
- Collagen was extracted using 6% acetic acid and analyzed for its structure and morphology through techniques like Fourier-transform infrared spectroscopy and scanning electron microscopy.
- The results showed no significant toxicity of the collagen on fibroblast cells, indicating high viability with a p-value of 0.754 (p>0.0025).
Article Abstract
Aim: This study aims to examine the toxicity of collagen extracted from gouramy fish scales () by evaluating its viability against baby hamster kidney fibroblasts-21.
Materials And Methods: Collagen was extracted from gouramy fish scales () with 6% acetic acid. Its results were analyzed using Fourier-transform infrared spectroscopy and freeze-dried technique. Its morphology then was analyzed with scanning electron microscope. Afterward, 3-(4.5-dimethylthiazole-2-yl)2.5-diphenyl tetrazolium bromide assay was conducted to compare cells with and without fish scale collagen treatment.
Results: Collagen extracted from gouramy fish scales had no influence statistically on cultured fibroblast cells with a statistical significance (2-tailed) value of0.754 (p>00025).
Conclusion: Collagen extracted from gouramy fish scales has high viability against BHK21 fibroblast cells.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5960791 | PMC |
| http://dx.doi.org/10.14202/vetworld.2018.506-510 | DOI Listing |
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