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http://dx.doi.org/10.1016/j.jns.2018.04.028 | DOI Listing |
Cureus
September 2024
Nephrology, Staten Island University Hospital, Staten Island, USA.
Nivolumab is an immune checkpoint inhibitor (ICI) that treats various malignancies. Although ICIs have proven efficacious, they can also have detrimental side effects. We present a case of nivolumab-induced quadriparesis mimicking Guillain-Barré syndrome in a patient with stage III squamous cell carcinoma (SCC) of the pharynx with a chronic tracheostomy, who presented after being found unconscious at home.
View Article and Find Full Text PDFAm J Case Rep
April 2024
Intensive Care Unit, UCL Namur University Hospital, Yvoir, Belgium.
BACKGROUND CRS (cytokine release syndrome) is a massive activation of the inflammatory system characterized by a supra-physiological rate of inflammatory cytokines. The interleukin 6 cytokine plays a central role in CRS. The main clinical sign of CRS is fever, but CRS can lead to multiple organ failure in severe cases.
View Article and Find Full Text PDFCureus
July 2023
Department of Pathology, Aretaieion University Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, GRC.
Nivolumab is an immune checkpoint inhibitor used in the treatment of several types of cancer. Among the adverse effects of this drug, immune-mediated colitis (IMC) has been described. However, in contrast to other checkpoint inhibitors, such as ipilimumab, drug-induced colitis due to nivolumab is not commonly reported.
View Article and Find Full Text PDFClin Case Rep
March 2023
Department of Nephrology Chang Gung Memorial Hospital, Linkou Taiwan.
Nivolumab belongs to immune checkpoint inhibitors (ICIs). ICIs-induced kidney injury is rare and acute interstitial nephritis (AIN) is the majority. A 58-year-old woman had gastric cancer treated with nivolumab.
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