A new alkylbenzoquinone named embeliquinone () together with five known compounds, lupeol (), 3--[6'--palmitoyl--d-glucosyl]-spinasta-7,22(23)-diene (), quercetin (), (2,3,4,8)-2-[(2')-2'-hydroxy-heneicosanoylamino]-heneicosane-1,3,4-triol-8-ene (), and -sitosterol-3---d-glucopyranoside () were isolated from the MeOH leaf extract of by using repeated open column chromatography techniques. The structure of the new compound was characterized by analyses of 1D- and 2D-NMR, and MS data. Embeliquinone () had moderate anti-cell proliferation activity against A549 cell line with the IC value of 21.8 μM. In addition, exhibited weak antibacterial activities against and with an MIC value of 206.0 μM in both cases.
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| http://dx.doi.org/10.1080/14786419.2018.1479703 | DOI Listing |
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b Institute of Natural Medicine , University of Toyama, Toyama , Japan.
A new alkylbenzoquinone named embeliquinone () together with five known compounds, lupeol (), 3--[6'--palmitoyl--d-glucosyl]-spinasta-7,22(23)-diene (), quercetin (), (2,3,4,8)-2-[(2')-2'-hydroxy-heneicosanoylamino]-heneicosane-1,3,4-triol-8-ene (), and -sitosterol-3---d-glucopyranoside () were isolated from the MeOH leaf extract of by using repeated open column chromatography techniques. The structure of the new compound was characterized by analyses of 1D- and 2D-NMR, and MS data. Embeliquinone () had moderate anti-cell proliferation activity against A549 cell line with the IC value of 21.
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