The aim of this study was to establish in vitro bench-tests of left atrial appendage occlusion (LAAo) devices regarding tug force, radial force and sealing capacity. Two LAAo devices, namely the WATCHMAN™ and the Occlutech, of three different sizes underwent testing in novel dedicated in vitro setups. Radial force was assessed in a commercial radial force tester. At baseline, tug force of the WATCHMAN™ was significantly higher when compared to Occlutech for all devices. Repeated resheathing resulted in a reduction of device-diameter in the WATCHMAN™ devices of max. 7.9%, whereas diameters of Occlutech occluders remained unchanged. Tug force was not significantly impacted by resheathing in both devices. At baseline, sealing capacity in a bench-test using silicone LAA-models did not differ between the devices. Resheathing lead to an in vitro loss of sealing capacity of the WATCHMAN™ devices, increasing with resheathing and resulting in a max. peridevice leak of 91.1 ± 7.9%. Radial force was higher for the Occlutech devices and decreased for WATCHMAN™ occluders after resheathing. The WATCHMAN™ occluder series showed progressive deformation, increased peridevice leakage and decreased radial force after resheathing, presumably as a result of diameter reduction. Tug force of the WATCHMAN™ was not impaired by resheathing and was significantly higher than that of the Occlutech device.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s10439-018-2057-z | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Altering the mechanical properties of self-assembled filaments through engineering of EspA bacterial protein.
Mater Today Bio
February 2025
Department of Chemical Engineering, Ben-Gurion University of the Negev, Beer Sheva, 8410501, Israel.
Protein-based biomaterials are in high demand due to their high biocompatibility, non-toxicity, and biodegradability. In this study, we explore the bacterial secreted protein A (EspA), which self-assembles into long extracellular filaments, as a potential building block for new protein-based biomaterials. We investigated the morphological and mechanical properties of EspA filaments and how protein engineering can modify them.
View Article and Find Full Text PDFRadial Tear of the Midbody in Complete Discoid Lateral Meniscus: A Case Report.
Cureus
December 2024
Department of Orthopedic Sports Medicine, Seifu Hospital, Sakai, JPN.
To the best of our knowledge, there are no reports on the results of the repair of radial tears of the midbody of the complete discoid lateral meniscus (DLM). A 14-year-old female underwent meniscal replacement with autologous tendon transplantation for early re-tear after repair of the radial tear in the midbody of complete DLM. Two years after the tendon transplantation, there was no effusion or swelling, and the patient was able to exercise completely without symptoms.
View Article and Find Full Text PDFA self-expandable nitinol frame for cable-driven parallel mechanisms in minimally invasive cardiovascular interventions.
J Mech Behav Biomed Mater
January 2025
Department of Biomedical Engineering, Toronto Metropolitan University, Toronto, Canada; Sunnybrook Research Institute, Toronto, Canada.
The integration of self-expandable nitinol frames with cable-driven parallel mechanisms offers a promising advancement in minimally invasive cardiovascular interventions. This study presents the design, fabrication, and verification of a miniaturized self-expandable nitinol frame to enhance catheter tip steerability and navigation within complex vascular anatomies. The frame is reduced in size for delivery through 7-8 Fr sheaths while accommodating diverse vascular diameters, allowing up to a maximum expansion of 15 mm.
View Article and Find Full Text PDFEvaluation of rapid evaporative ionization mass spectrometry (REIMS) for the prediction of slice shear force and quality grades in beef longissimus lumborum steaks.
Meat Sci
January 2025
Department of Animal and Food Sciences, Texas Tech University, Lubbock, TX 79409, USA. Electronic address:
Steak samples were collected from the longissimus lumborum muscles of beef carcasses (Canada AA, n = 1505; Canada AAA, n = 1363) over a 3-year period. Steaks were aged for 14 d, and tenderness was determined by slice shear force (SSF). Metabolomic profiling of beef samples was performed using rapid evaporative ionization mass spectrometry (REIMS) (N = 2853).
View Article and Find Full Text PDFEffect of induced extrinsic and intrinsic hand and forearm muscular fatigue on the control of finger force during piano playing.
Hum Mov Sci
January 2025
Department of Biomedical Engineering, College of Engineering, National Cheng Kung University, Tainan, Taiwan; Institute of Allied Health Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan; Medical Device Innovation Center, National Cheng Kung University, Tainan, Taiwan; Department of Occupational Therapy, College of Medicine, National Cheng Kung University, Tainan, Taiwan. Electronic address:
This study aimed to investigate the effect of hand muscle fatigue on finger control and force efficiency during piano performance, which is crucial for skilled piano playing among professional pianists engaged in prolonged periods of high-intensity practice or concert preparation. Thirty-one professional pianists were recruited as participants. This study was divided into three sequential experimental parts: pre-fatigue test, fatigue protocol, and post-fatigue test.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!