AI Article Synopsis

  • Tubulocystic renal cell carcinoma (TC-RCC) is recognized as a unique subtype by the 2016 WHO classification, mainly affecting men.
  • Radiological imaging shows TC-RCC typically presents as multilocular cystic lesions categorized as Bosniak classification II-IV, with distinctive pathological features like small cysts or tubular structures.
  • Differentiating TC-RCC from other similar cystic tumors is complex and challenging, prompting this review to address the importance of radiological findings in distinguishing TC-RCC during diagnosis.

Article Abstract

Tubulocystic renal cell carcinoma (TC-RCC) has been classified as an independent subtype according to the 2016 World Health Organization (WHO) classification. It is a rare subtype that predominantly affects men. Although few in number, radiological imaging reports have suggested that TC-RCC is characterized by multilocular cystic lesions, which are categorized as the Bosniak classification II-IV, with signature pathological characteristics comprising numerous small cysts or a tubular structure. The Bosniak classification system facilitates patient management; however, the differentiation of cystic tumors exhibiting similar imaging findings remains impossible; in fact, the differentiation of multilocular cystic RCC, adult cystic nephroma, and mixed epithelial and stromal tumor remains challenging. This review aims to discuss TC-RCC with a focus on implications of radiological findings in the differential diagnosis of TC-RCC.

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http://dx.doi.org/10.1007/s00261-018-1643-8DOI Listing

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