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Post-mortem diagnosis of malaria in decomposed and embalmed body.
Forensic Sci Med Pathol
December 2024
Chair and Department of Forensic Medicine, Jagiellonian University Medical College, Kraków, Poland.
The diagnosis of malaria during the autopsy of a decomposed corpse may prove challenging. Macroscopic changes are non-specific and may include, among others, cerebral oedema, pulmonary oedema, hepatosplenomegaly and, on occasion, the presence of petechiae. The most effective diagnostic tools for malaria are the examination of blood smears and the use of rapid immunochromatographic tests.
View Article and Find Full Text PDFA new approach to assess post-mortem interval: A machine learning-assisted label-free ATR-FTIR analysis of human vitreous humor.
Spectrochim Acta A Mol Biomol Spectrosc
February 2025
Department of Life and Environmental Sciences, Polytechnic University of Marche, Via Brecce Bianche, 60131 Ancona, Italy.
A crucial issue in forensics is determining the post-mortem interval (PMI), the time between death and the finding of a body. Despite various methods already employed for its estimation, only approximate values are currently achievable. Vitreous humor (VH) is an avascular tissue between the lens and the retina, mainly composed by a collagen fibers network, hyaluronic acid, and hyalocytes.
View Article and Find Full Text PDFChanges in tissues and organs through PMCTA carrier substances.
Int J Legal Med
January 2025
University Center of Legal Medicine, University Hospital of Vaud, Chemin de La Vulliette 4, CH - 1000, Lausanne, Switzerland.
Article Synopsis
- Lipophilic contrast agents, primarily paraffin oil, and iodine-based hydrophilic contrast media like PEG are the main substances used in post-mortem CT angiography, yet their effects on human tissues are not fully understood.
- A study was conducted to compare the preservation characteristics of PEG 200 and oil on cadaveric tissues during a forensic autopsy, with samples evaluated at various intervals.
- Results indicated that samples in PEG quickly solidified and retained good diagnostic quality, while oil-preserved samples exhibited significant decomposition, highlighting the importance of selecting the appropriate contrast agent for forensic investigations.*
Incidental detection of aluminum phosphide in abdominal subcutaneous fat- a rare reporting of chemical analysis findings in poisoning cases.
Forensic Sci Med Pathol
October 2024
Department of Forensic Medicine and Toxicology, Maharishi Markandeshwar Institute of Medical Sciences and Research, Mullana (Ambala), Haryana, India.
Article Synopsis
- Aluminum phosphide (AlP) is a toxic substance readily available in unregulated markets in developing countries, posing serious health risks due to lack of antidotes.
- The text describes three unique cases where AlP was detected in abdominal subcutaneous fat postmortem, highlighting a previously unreported method for detection amid challenges like decomposition and other interfering substances.
- Gas chromatography-mass spectrometry (GC-MS) analysis confirmed AlP presence in both routine viscera and abdominal fat, suggesting that subcutaneous fat can effectively be used for toxicological testing, even in decomposed bodies.
Artefacts due to putrefactive gas production - an overview.
Med Sci Law
January 2025
Adelaide School of Biomedicine, The University of Adelaide, Australia.
Article Synopsis
- Autolytic and putrefactive processes significantly alter soft tissues and organs after death, complicating forensic evaluations.
- Common occurrences include fluids leaking from the nose and mouth, which can be misinterpreted as pre-death bleeding, and the unusual phenomenon of putrefactive 'rigor mortis' causing limb extension due to gas buildup.
- Other effects include skin distension leading to the reopening of surgical wounds, increased abdominal pressure potentially causing hernias, and the risk of confusing postmortem gas with trauma or air embolism in imaging scans.
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