AI Article Synopsis
- Mutation is a key driver of evolution, and studying its rate can shed light on how species diverge, though this is understudied in many organisms.
- Previous research on ciliated protozoa indicates they have very low mutation rates.
- Using advanced genome sequencing techniques, this study examines mutation rate variations in three related ciliate species and finds minimal differences, reinforcing the notion that ciliates have extremely low mutation rates.
Article Abstract
Mutation is one of the most fundamental evolutionary forces. Studying variation in the mutation rate within and among closely-related species can help reveal mechanisms of genome divergence, but such variation is unstudied in the vast majority of organisms. Previous studies on ciliated protozoa have found extremely low mutation rates. In this study, using mutation-accumulation techniques combined with deep whole-genome sequencing, we explore the germline base-substitution mutation-rate variation of three cryptic species in the species complex-, , and We find that there is extremely limited variation of the mutation rate and spectrum in the three species and confirm the extremely low mutation rate of ciliates.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027866 | PMC |
| http://dx.doi.org/10.1534/g3.118.200420 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!