Deriving from logical and mechanical interactions between DNA strands and complexes, DNA-based artificial reaction networks (RNs) are attractive for their high programmability, as well as cascading and fan-out ability, which are similar to the basic principles of electronic logic gates. Arising from the dream of creating novel computing mechanisms, researchers have placed high hopes on the development of DNA-based dynamic RNs and have strived to establish the basic theories and operative strategies of these networks. This review starts by looking back on the evolution of DNA dynamic RNs; in particular' the most significant applications in biochemistry occurring in recent years. Finally, we discuss the perspectives of DNA dynamic RNs and give a possible direction for the development of DNA circuits.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522144 | PMC |
| http://dx.doi.org/10.1016/j.tibs.2018.04.010 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
In Vivo Nitrosative Stress-Induced Expression of a Photolyase Promotes Vibrio cholerae Environmental Blue Light Resistance.
Mol Microbiol
January 2025
Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Bacterial pathogens possess a remarkable capacity to sense and adapt to ever-changing environments. For example, Vibrio cholerae, the causative agent of the severe diarrheal disease cholera, thrives in aquatic ecosystems and human hosts through dynamic survival strategies. In this study, we investigated the role of three photolyases, enzymes that repair DNA damage caused by exposure to UV radiation and blue light, in the environmental survival of V.
View Article and Find Full Text PDFIn Vivo visualization of microplastic degradability and intestinal functional responses in a plastivore insect.
J Hazard Mater
January 2025
School of Energy and Environment and State Key Laboratory of Marine Pollution, City University of Hong Kong, Kowloon 999077, Hong Kong; Research Centre for the Oceans and Human Health, City University of Hong Kong Shenzhen Research Institute, Shenzhen 518057, China. Electronic address:
The plastivore insect Tenebrio molitor demonstrates significant potential for the rapid biodegradation and bioremediation of micro(nano)plastics. However, real-time visualization of the digestive degradation and removal of microplastics (MPs) during intestinal transit, along with the associated in vivo intestinal functional responses, remains challenging. Here, we developed second near-infrared (NIR-II) window aggregated-induced emission (AIE) MPs of two sizes (29.
View Article and Find Full Text PDFKey concepts and a world-wide look at plant recruitment networks.
Biol Rev Camb Philos Soc
December 2024
Andalusian Interuniversity Institute for Earth System Research (IISTA), Avenida del Mediterráneo, Granada, 18071, Spain.
Plant-plant interactions are major determinants of the dynamics of terrestrial ecosystems. There is a long tradition in the study of these interactions, their mechanisms and their consequences using experimental, observational and theoretical approaches. Empirical studies overwhelmingly focus at the level of species pairs or small sets of species.
View Article and Find Full Text PDFMR perfusion characteristics of pseudoprogression in brain tumors treated with immunotherapy - a comparative study with chemo-radiation induced pseudoprogression and radiation necrosis.
J Neurooncol
December 2024
Advanced Neuroimaging Laboratory, The Affiliated Yuebei People's Hospital of Shantou University Medical College, Shaoguan, Guangdong Province, China.
Purpose: Pseudoprogression is an atypical imaging pattern of response to immunotherapy in patients with brain tumors. MR perfusion studies in this field are limited. The purpose of our study is to compare the perfusion features between pseudoprogression lesions in malignant gliomas and brain metastases treated with immunotherapy (iPsP) and the pseudoprogression after chemo-radiation therapy and radiation necrosis after radiation treatment (ChR-PsP & RN).
View Article and Find Full Text PDFAcculturating Pathway to Practice: A Conceptual Framework of Factors Influencing Foreign-Educated Physicians (FEPs) Transitioning to Nursing as a Second Career.
Hisp Health Care Int
December 2024
Nevada State University, Henderson, NV, USA.
Many foreign-educated physicians (FEPs) are transitioning to licensed registered nurses (RNs) in the United States, a process that helps decrease the nursing shortage. There is a gap in knowledge regarding how they transform from medical to nursing professionals. This information could assist FEPs to effectively transition into the nursing role.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!