AI Article Synopsis
- Multiple sclerosis (MS) is believed to have an autoimmune cause, with evidence suggesting environmental factors like geographical location and Vitamin D levels play a role in its development.
- Clinical trials are being conducted to investigate the impact of a Vitamin D-rich diet and UVB treatment on the incidence, severity, and progression of MS.
- This review focuses on summarizing the existing research on how UVB light and Vitamin D relate to the clinical features of MS based on epidemiological studies and clinical trials.
Article Abstract
Multiple sclerosis (MS) is a disease of presumed auto-immune origin. Long-standing observations such as the correlation between MS incidence and geographical latitude or the levels of Vitamin D (Vit D) in the serum have implicated the environmental factors UVB radiation and diet in the etiology of the disease. Clinical trials have been conducted and are currently underway to elucidate whether a Vit D enriched diet or treatment with UVB can influence MS incidence, -severity, and -progression, as well as the ideal time point for treatment. This review summarizes the current scientific knowledge to the environmental factors UVB-light and Vit D concerning the clinical aspects of MS in epidemiological studies and clinical trials.
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| http://dx.doi.org/10.1016/j.jneuroim.2018.05.006 | DOI Listing |
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