Background And Purpose: Sterile compounding skills are essential components of a professional pharmacy curriculum. The theory of desirable difficulties has been used to facilitate deeper learning of material in other disciplines, but has not been described in pharmacy sterile compounding instruction. The purpose of this work was to evaluate whether challenges introduced in sterile compounding would act as desirable difficulties and result in greater student confidence in their sterile compounding competency.
Educational Activity And Setting: Students in the fourth semester of Pharmacy Skills and Applications, a laboratory-based skills course, were presented with challenges in sterile compounding and were asked to complete a questionnaire rating their confidence and describing their experience.
Findings: The majority (92.8%) of students reported that the activity increased their confidence in their sterile compounding skills. Students' open-ended responses suggested that most of the knowledge gained was strategic in nature.
Discussion: The results of this activity met the instructors' initial goals by positively impacting students' confidence in their ability to overcome challenges with sterile products compounding. Course instructors may explore additional skills in which to introduce desirable difficulties in order to build student confidence.
Summary: Course instructors were pleased with the implementation and results of this desirable difficulties activity and plan to continue its use again in future semesters. Incorporating more real-world challenges throughout the skills-lab course may be beneficial to student learning and confidence. With thoughtful planning, faculty at other institutions can readily incorporate similar activities within their own courses.
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http://dx.doi.org/10.1016/j.cptl.2017.12.018 | DOI Listing |
Eur J Hosp Pharm
January 2025
School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, Dublin, Ireland
Objectives: This paper combines the concepts of design thinking and benchmarking in an aseptic manufacturing context. Design thinking is a problem-solving approach that aims to understand user needs, generate ideas, prototypes and test solutions. There are no published examples in the Irish healthcare setting.
View Article and Find Full Text PDFEur J Hosp Pharm
January 2025
Pharmacy Department, Hospices Civils de Lyon, Groupement Hospitalier Nord, Lyon, France
Objectives: Acceleration of the haemostasis process after dermatological surgery predominantly relies on mechanical methods, such as the use of sutures or staples. To our knowledge, there is currently no commercialised haemostatic agent for this specific application. Due to the protein precipitation properties of the 50% (w/v) aluminium chloride hexahydrate solution, its physicochemical stability and maintenance of sterility over a 6 month period were assessed.
View Article and Find Full Text PDFAnn Pharm Fr
January 2025
Service de pharmacotechnie Pellegrin, CHU Bordeaux, place Amélie-Raba-Léon, 33000 Bordeaux, France.
Objectives: Training of pharmacy technicians in non-sterile compounding unit must meet the requirements of the French Good Manufacturing Practices. Our current training program is composed of one week companionship preceded by a theoretical course and do not allow the acquisition of all the skills and knowledge required. The formation load over the pharmacist and technician also increase due to an important turnover among the technicians.
View Article and Find Full Text PDFAllergy Asthma Proc
January 2025
The United States Pharmacopeia (USP) Chapter 797 provides critical standards for compounding sterile preparations to ensure patient safety and medication efficacy. The latest revision, effective November 1, 2023, introduces updates particularly relevant to the compounding of allergenic extracts, which emphasizes stringent compliance measures. This article aims to review the key updates to USP Chapter 797, outline the compliance requirements for personnel and facilities, and offer strategies for staying current with these practice guidelines, leveraging resources from professional organizations such as American College of Allergy, Asthma, and Immunology and American Academy of Allergy, Asthma, and Immunology.
View Article and Find Full Text PDFZhongguo Zhong Yao Za Zhi
October 2024
Key Laboratory of Modern Chinese Medicine Formulations, Ministry of Education, Jiangxi University of Chinese Medicine Nanchang 330004, China.
Since ancient times, traditional Chinese medicine pills have occupied a key position among different dosage forms of traditional Chinese medicine. With the aims of comprehensively improving the overall quality and innovating key technologies in the manufacturing of the pills, this article elaborates on the principles and new technology applications in pulverizing, sterilization, agglomeration, forming, and drying. In addition, modern technologies such as biosensing, image analysis, texture property evaluation, and moisture analysis can comprehensively and accurately characterize the quality of key materials in the manufacturing of traditional Chinese medicine pills, thereby achieving strict control over the quality of raw materials, intermediates, and final products and further monitoring and optimizing the entire production process of pill preparations.
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