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Long-term impact of COVID-19-related nonpharmaceutical interventions on tuberculosis: an interrupted time series analysis using Bayesian method.
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Beijing Key Laboratory of Antimicrobial Agents/Laboratory of Pharmacology, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Background: The implementation of non-pharmaceutical interventions (NPIs) during the COVID-19 pandemic may inadvertently influence the epidemiology of tuberculosis (TB). (TB). However, few studies have explored how NPIs impact the long-term epidemiological trends of TB.
View Article and Find Full Text PDFIdentification of 6,8-ditrifluoromethyl halogenated phenazine as a potent bacterial biofilm-eradicating agent.
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Department of Pharmaceutical & Biomedical Sciences, College of Pharmacy, University of Georgia, Athens, Georgia 30602, USA.
Bacterial biofilms are surface-attached communities consisting of non-replicating persister cells encased within an extracellular matrix of biomolecules. Unlike bacteria that have acquired resistance to antibiotics, persister cells enable biofilms to demonstrate innate tolerance toward all classes of conventional antibiotic therapies. It is estimated that 50-80% of bacterial infections are biofilm associated, which is considered the underlying cause of chronic and recurring infections.
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Department of Rheumatology, Shalamar Institute of Health Sciences, Lahore, Pakistan.
Primary Sjogren's syndrome (pSS) typically presents with Sicca symptoms xerostomia and xeropthalmia. This study highlights atypical presentations of Primary Sjogren's syndrome posing diagnostic and therapeutic challenges. Four female patients (median age 30 years, IQR = 15.
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