Ligand-Free Iron-Catalyzed Carbon(sp)-Carbon(sp) Cross-Coupling of Alkenyllithium with Vinyl Halides.

J Org Chem

Department of Chemistry and State Key Laboratory of Synthetic Chemistry , The Chinese University of Hong Kong, Shatin, New Territories , Hong Kong SAR , China.

Published: June 2018

An efficient ligand-free iron-catalyzed cross-coupling reaction involving alkenyllithium and vinyl iodides was developed to form diene species in moderate to good yields. This new iron-catalyzed cross-coupling reaction provides a mild, inexpensive, and environmentally friendly avenue toward synthesis of diversified diene derivatives.

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Source
http://dx.doi.org/10.1021/acs.joc.8b00510DOI Listing

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