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Modulation of germinal center and antibody dynamics via ipsilateral versus contralateral immunization against SARS-CoV-2.
J Immunol
March 2025
Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
Human clinical trials have reported immunological outcomes can differ between ipsilateral (same side) and contralateral (alternate sides) prime-boost vaccination. However, our mechanistic understanding of how keeping or shifting the anatomical sites of immunization impacts the resultant germinal centers (GCs) and antibody responses is limited. Here, we use an adjuvanted SARS-CoV-2 spike vaccine to dissect GC dynamics in draining lymph nodes and serological outcomes following ipsilateral or contralateral prime-boost vaccination in C57BL/6 mice.
View Article and Find Full Text PDFCytochrome c and Ouabain Binding Site of Na,K-ATPase.
Cell Biochem Biophys
March 2025
Georgian National University, 9 Tsinandali Str., Tbilisi, Georgia.
Na,K-ATPase is an electrogenic pump found in cell plasma membranes that acts as the basic unit of animal life. This enzyme is highly susceptible to cardiotonic steroid (CTS) inhibition. The role of Na,K-ATPase in signaling has introduced a novel viewpoint regarding the enzyme's function, as the ouabain-binding site is involved in several physiological processes.
View Article and Find Full Text PDFMetal Organic Chemical Vapor Deposition of Hybrid Perovskites.
J Am Chem Soc
March 2025
Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-3290, United States.
Semiconductor devices often rely on high-purity materials and interfaces achieved through vapor- and vacuum-based fabrication methods, which can enable precise compositional control down to single atomic layers. Compared to groups IV and III-V semiconductors, hybrid perovskites (HPs) are an emergent class of semiconductor materials with remarkable solution processability and compositional variability that have facilitated rapid experimentation to achieve new properties and progress toward efficient devices, particularly for solar cells. Surprisingly, vapor deposition techniques for HPs are substantially less developed, despite the complementary benefits that have secured vapor methods as workhorse tools for semiconductor fabrication.
View Article and Find Full Text PDFReaction Mechanism and Kinetic Model of the Transformation of Iron Monosulfide Thin Films into Pyrite Films.
J Phys Chem C Nanomater Interfaces
March 2025
Dpto. de Física de Materiales, Facultad de Ciencias, Universidad Autónoma de Madrid, Francisco Tomás y Valiente 7, E-28049 Madrid, Spain.
This work presents a comprehensive reaction and kinetic model of the pyrite thin films formation by sulfuration of Fe monosulfides when a molecular sulfur (S) atmosphere is used. This investigation completes the results already published on the explanation and interpretation of the sulfuration process that transforms metallic iron into pyrite. It was previously shown that the monosulfide species (i.
View Article and Find Full Text PDFNew strategy for integration of anaerobic side-stream reactor with mainstream B-stage nitritation for short-cut nitrogen removal with granulation.
Water Environ Res
March 2025
School of Civil and Environmental Engineering, Cornell University, Ithaca, New York, USA.
This study reported a successful mainstream B-stage nitritation reactor with sludge granulation that incorporated a side-stream anaerobic reactor to treat municipal wastewater A-stage effluent. With influent COD/N and COD/P ratios of 2.60 and 27.
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