Background: Misuse of synthetic antibiotics in livestock leads to the transfer of antibiotic resistant pathogens into humans and deposits toxic residues in meat and milk. There is therefore an urgent need for safe and viable alternative approaches to improve the nutrition and wellbeing of farm animals. An alternative source that has been widely exploited is Traditional Chinese Herbal Medicine (TCHM). These herbs contain several but less toxic bioactive compounds which are generally regarded as biodegradable. Recently, advances in the knowledge of the importance of TCHM have led to a rapid increase in its production and hence, increasing the amount of by-products generated. Such by-products have become a serious environmental challenge because producers regard them as industrial waste and discard them directly. This review summarizes scientific findings on the bioactive compounds in TCHM and TCHM by-products, discusses functional dietary patterns and outlines challenges that may hinder full utilization of TCHM by-products in animal production.
Methods: Information for this review was obtained through scientific databases and websites such as Pubmed and Google scholar from 2004 to 2017 using experimental studies on bioactive compounds in TCHM and their effects in animal production.
Results: Studies have shown that TCHM by-products contain high amounts of bioactive compounds which confer several nutritional and health benefits to animals and thus could be incorporated as feed additives.
Conclusion: The findings for this review indicate that TCHM by-products apart from being a good alternative for synthetic antibiotics could also minimize the current environmental challenges associated with its disposal.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.2174/1389200219666180523102920 | DOI Listing |
Front Cell Infect Microbiol
January 2025
Mkelly Biotech Pvt Ltd., Mohali, Punjab, India.
Background: The rise of antibiotic-resistant pathogens has intensified the search for novel antimicrobial agents. This study aimed to isolate from local soil samples and evaluate its antimicrobial properties, along with optimizing the production of bioactive compounds.
Methods: Soil samples were collected from local regions, processed, and analysed for Streptomyces strains isolation using morphological characteristics and molecular identification through 16S rRNA gene PCR assay.
Onco Targets Ther
January 2025
Affiliated Yongkang First People's Hospital and School of Pharmaceutical Sciences, Hangzhou Medical College, Hangzhou, Zhejiang, People's Republic of China.
Background: TiaoShenGongJian (TSGJ) decoction, a traditional Chinese medicine for breast cancer, has unknown active compounds, targets, and mechanisms. This study identifies TSGJ's key targets and compounds for breast cancer treatment through network pharmacology, machine learning, and experimental validation.
Methods: Bioactive components and targets of TSGJ were identified from the TCMSP database, and breast cancer-related targets from GeneCards, PharmGkb, and RNA-seq datasets.
Indian J Clin Biochem
January 2025
Department of Biochemistry, College of Medicine and J.N.M Hospital, WBUHS, Kalyani, West Bengal 741235 India.
Radiation therapy uses ionizing radiation (IR) to kill cancer cells. However, during radiotherapy normal cells are also damaged and killed by the generation of reactive oxygen species. Polyphenolic compounds are known to mitigate the damaging effects of radiation.
View Article and Find Full Text PDFRSC Adv
January 2025
Department of Pharmaceutical Sciences, Maharshi Dayanand University Rohtak 124001 India
Cancer is a major global concern. Despite considerable advancements in cancer therapy and control, there are still large gaps and requirements for development. In recent years, various naturally occurring anticancer drugs have been derived from natural resources, such as alkaloids, glycosides, terpenes, terpenoids, flavones, and polyphenols.
View Article and Find Full Text PDFRSC Adv
January 2025
Regenerative Medicine and Tissue Repair Material Research Center, HuangpuInstitute of Materials 88 Yonglong Avenue of Xinlong Town Guangzhou 511363 P. R. China.
As a well-known aromatic herb rich in various bioactive molecules, the extract of is widely used in cosmetics. However, the extraction process for is far from perfect. Moreover, the water- and oil-soluble components are too complex to be compatible with each other.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!