Safety concerns persist for long-term pediatric fluoroquinolone use. Seventy children (median age, 2.1 years) treated with levofloxacin 10-20 mg/kg once daily for multidrug-resistant tuberculosis (median observation time, 11.8 months) had few musculoskeletal events, no levofloxacin-attributed serious adverse events, and no Fridericia-corrected QT interval >450 ms. Long-term levofloxacin was safe and well tolerated.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233673 | PMC |
| http://dx.doi.org/10.1093/cid/ciy416 | DOI Listing |
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