Objective: To summarize the current research progress of three-dimensional (3D) printing technique for spinal implants manufacture.
Methods: The recent original literature concerning technology, materials, process, clinical applications, and development direction of 3D printing technique in spinal implants was reviewed and analyzed.
Results: At present, 3D printing technologies used to manufacture spinal implants include selective laser sintering, selective laser melting, and electron beam melting. Titanium and its alloys are mainly used. 3D printing spinal implants manufactured by the above materials and technology have been successfully used in clinical. But the problems regarding safety, related complications, cost-benefit analysis, efficacy compared with traditional spinal implants, and the lack of relevant policies and regulations remain to be solved.
Conclusions: 3D printing technique is able to provide individual and customized spinal implants for patients, which is helpful for the clinicians to perform operations much more accurately and safely. With the rapid development of 3D printing technology and new materials, more and more 3D printing spinal implants will be developed and used clinically.
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http://dx.doi.org/10.7507/1002-1892.20160236 | DOI Listing |
Neuromodulation
January 2025
Department of Anesthesiology, University of Wisconsin, Madison, WI, USA.
Objectives: Past studies have shown the efficacy of spinal targeted drug delivery (TDD) in pain relief, reduction in opioid use, and cost-effectiveness in long-term management of complex chronic pain. We conducted a survey to determine treatment variables associated with patient satisfaction.
Materials And Methods: Patients in a single pain clinic who were implanted with Medtronic pain pumps to relieve intractable pain were identified from our electronic health record.
Biomater Adv
December 2024
Key Laboratory for Ultrafine Materials of Ministry of Education, Frontiers Science Center for Materiobiology and Dynamic Chemistry, Engineering Research Center of Biomedical Materials of Ministry of Education, School of Materials Science and Engineering, East China University of Science and Technology, Shanghai 200237, PR China. Electronic address:
Spinal cord injury (SCI) results in electrophysiological and behavioral dysfunction. Electrical stimulation (ES) is considered to be an effective treatment for mild SCI; however, ES is not applicable to severe SCI due to the disruption of electrical conduction caused by tissue defects. Therefore, the use of conductive materials to fill the defects and restore electrical conduction in the spinal cord is a promising therapeutic strategy.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Orthopedics, University-Town Hospital of Chongqing Medical University, Chongqing, China.
Metal implants are commonly used in clinical practice. However, little is known regarding the prevalence of metal implants. Therefore, this study aimed to evaluate the prevalence of metal implants in the United States (US) among individuals aged ≥ 40 years.
View Article and Find Full Text PDFACS Appl Mater Interfaces
January 2025
Department of Bioengineering, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, United States.
Current limitations in implant design often lead to trade-offs between minimally invasive surgery and achieving the desired post-implantation functionality. Here, we present an artificial intelligence inverse design paradigm for creating deployable implants as planar and tubular thermal mechanical metamaterials (thermo-metamaterials). These thermo-metamaterial implants exhibit tunable mechanical properties and volume change in response to temperature changes, enabling minimally invasive and personalized surgery.
View Article and Find Full Text PDFA A Pract
January 2025
From the Department of Pain Management, Cleveland Clinic, Cleveland, Ohio.
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