AI Article Synopsis
- The study aimed to assess how the timing of exercise impacts blood sugar control in patients with Type 2 Diabetes (T2D) who are on metformin.
- 26 patients participated in the study, undergoing tests after metformin alone and after high-intensity interval training at different times post-breakfast (30, 60, and 90 minutes).
- Results showed that exercising at any of the three times led to a significant drop in glucose and insulin levels compared to metformin alone, highlighting the importance of timing for exercise in managing T2D.
Article Abstract
Objective: The purpose of the study was to examine the acute effects of the timing of exercise on the glycemic control during and after exercise in T2D.
Methods: This study included 26 T2D patients (14 women and 12 men) who were treated with metformin. All patients were tested on four occasions: metformin administration alone (Metf), high-intensity interval training (HIIT) performed at 30 minutes (EX30), 60 minutes (EX60), and 90 minutes (EX90) postbreakfast, respectively. Glucose, insulin, and superoxide dismutase (SOD) activity were examined.
Results: Glucose decreased significantly after the exercise in EX30, EX60, and EX90. Compared with Metf, the decline in glucose immediately after the exercise was larger in EX30 (-2.58 mmol/L; 95% CI, -3.36 to -1.79 mmol/L; < 0.001), EX60 (-2.13 mmol/L; 95% CI, -2.91 to -1.34 mmol/L; < 0.001), and EX90 (-1.87 mmol/L; 95% CI, -2.65 to -1.08 mmol/L; < 0.001), respectively. Compared with Metf, the decrease in insulin was larger in EX30 and EX60 (both < 0.001).
Conclusions: Timing of exercise is a factor to consider when prescribing exercise for T2D patients treated with metformin. This trial is registered with ChiCTR-IOR-16008469 on 13 May 2016.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896215 | PMC |
| http://dx.doi.org/10.1155/2018/2483273 | DOI Listing |
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