AI Article Synopsis
- A multidrug-resistant (MDR) strain was discovered from a urine sample in 2006, containing a specific gene within a chromosomal Tn-like class 3 integron.
- The study identified two mutations in quinolone-resistance-determining regions (QRDRs), contributing to the strain's resistance.
- Researchers report a new, full-length class 3 integron that, along with QRDR mutations, likely played a role in the strain's MDR characteristics.
Article Abstract
A multidrug-resistant (MDR) strain was isolated in 2006 from a urine sample. The isolate harbored the gene, which was located in a chromosomal Tn-like class 3 integron as a gene cassette array of Two mutations in and one mutation in were detected in quinolone-resistance-determining regions (QRDRs). We report a full-length, novel, -carrying class 3 integron. This integron, together with mutations in QRDRs, could have influenced the MDR phenotype.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105817 | PMC |
| http://dx.doi.org/10.1128/AAC.00701-18 | DOI Listing |
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