AI Article Synopsis
- Vascularized composite allograft (VCA) transplantation is an emerging area, with a study analyzing OPTN VCA waiting list data from July 2014 to February 2018.
- This study revealed 54 candidates were added to the VCA waiting list, with a majority being males (53.7%), primarily white (79.6%), and aged 18-44 (70.4%), and 22 of these candidates received deceased donor VCA transplants.
- The waiting times for VCA transplants differ significantly among candidates, highlighting an evolving field that requires further research to understand disparities in access and patient needs.
Article Abstract
Background: Vascularized composite allograft (VCA) transplantation is a developing area in the field of transplantation.
Methods: This study used Organ Procurement and Transplantation Network (OPTN) VCA waiting list and transplant data from July 3, 2014 through February 28, 2018, to characterize the OPTN VCA waiting list in terms of composition, removal patterns, waiting time, resulting transplants, and trends over time.
Results: Between implementation of the OPTN VCA waiting list on July 3, 2014 and February 28, 2018, 54 candidates-53.7% were male, 79.6% were white, and 70.4% aged 18 to 44 years-were added to the OPTN VCA waiting list. Of these, 22 received deceased donor VCA transplants (6 bilateral upper limb, 4 unilateral upper limb, 5 craniofacial, 1 scalp, 1 abdominal wall, 1 penile, and 4 uterine), and 6 received living donor uterine transplants. Registrations increased in 2016 after uterine and penile transplants were introduced in the United States, resulting in a large shift in the composition of the VCA waiting list. Waiting times for VCA candidates vary greatly, with some VCA candidates receiving deceased donor transplants quickly and others waiting more than 3 years before transplantation.
Conclusions: The field of VCA transplantation and the composition of the OPTN VCA waiting list are evolving rapidly. Additional research is needed to understand these changes and investigate whether differences in need or differences in access have resulted in the variation seen on the VCA waiting list.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1097/TP.0000000000002232 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Efficacy and Safety of a Desensitization Treatment With Rituximab and Immunoglobulin in Hyperimmunized Patients Awaiting a Cadaveric Kidney Transplantation.
Transplant Proc
January 2025
Servicio de Nefrología, Hospital Universitario La Paz, Madrid, Spain.
Background: Patients on a kidney transplant waiting list with antibodies against more than 80% of a panel reactive antibody (PRA) are difficult to transplant, even with national or regional programs. Desensitization treatment with high-dose intravenous immunoglobulin and rituximab could be offered to patients with a long waiting time for a cadaveric donor to improve their odds of finding a kidney.
Methods: This was a retrospective, single-center study including all hyperimmunized patients on the waiting list for a cadaveric kidney donor who received a desensitization treatment between 2010 and 2020.
[The exploratory meeting: Action research on the perspective of care recipients].
Tijdschr Psychiatr
January 2025
Background: Mental health care (MHC) is under pressure due to increased demands and limited capacity, resulting in long waiting lists. To improve accessibility, Mental Health Centers (MCs) were established in Central and West-Brabant starting in 2021, with the exploratory meeting (EM) as the first step.
Aim: To gain insight into citizens’ experiences with the EM, the flow to appropriate care, and contribution of action research to this process.
Effects of Dry Needling on Gastrocnemius Muscle Spasticity and Gait in Patients with Multiple Sclerosis: A Pilot Randomized Controlled Trial.
Med Acupunct
October 2024
Department of Physiatry and Nursing, Faculty of Health Sciences, University of Zaragoza, Zaragoza, Spain.
Objective: Spasticity is a common complication in patients with multiple sclerosis (pwMS). The present study aimed to evaluate the clinical, biomechanical, and functional effects of dry needling (DN) in treating gastrocnemius muscle spasticity in pwMS.
Materials And Methods: A pilot single-blinded randomized controlled trial was carried out.
Stakeholder prioritization preferences for individuals awaiting hip and knee arthroplasty.
Bone Joint J
January 2025
Institute of Applied Health Sciences, University of Aberdeen, Aberdeen, UK.
Aims: Prolonged waits for hip and knee arthroplasty have raised questions about the equity of current approaches to waiting list prioritization for those awaiting surgery. We therefore set out to understand key stakeholder (patient and surgeon) preferences for the prioritization of patients awaiting such surgery, in order to guide future waiting list redesign.
Methods: A combined qualitative/quantitative approach was used.
The burden of medical contraindications to corneal donation: Time for review.
PLOS Glob Public Health
December 2024
Laboratory Biology, Engineering and Imaging for Ophthalmology, Health Innovation Campus, Faculty of Medicine, University Jean Monnet, Saint-Etienne, France.
Corneal graft (keratoplasty) is the most common allograft in the world, but the imbalance between the number of donors and the number of patients waiting for transplants is abysmal on a global scale and varies enormously from one country to another. The risk of transmission of systemic diseases from donor to recipient is demonstrably low. In over 50 years and an estimated 2.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!