Three new polyketides from sp. ZJ-M-5 by the OSMAC strategy.

J Asian Nat Prod Res

a Key Laboratory of Structure-Based Drug Design & Discovery (Shenyang Pharmaceutical University), Ministry of Education , Shenyang Pharmaceutical University, Shenyang 110016 , China.

Published: July 2019

Three new compounds, ascotrichols A-B () and ascotrichrone A (), along with two known isocoumarin derivatives (), were isolated from the solid culture of a sea mud-derived fungus, sp. ZJ-M-5 on rice media. The structures were elucidated by extensive spectroscopic analyses, including 1D and 2D NMR data, and the absolute configurations were determined by electronic circular dichroism and biogenetic correlation.

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http://dx.doi.org/10.1080/10286020.2018.1471066DOI Listing

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