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The Toronto Tele-Retinal Screening Program for the Elderly in Long-Term Care: A Pilot Project.
Clin Ophthalmol
December 2024
Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
Objective: To report the results and feasibility of a pilot expansion of the Toronto Tele-Retinal Screening Program in an elderly long-term care home.
Methods: Long term care patients with Type II diabetes mellitus (DM) were screened between April 1, 2022, and July 1, 2022. Demographic and health data were collected through surveys.
Fabrication of three implant-supported crowns using a digital workflow: a case report.
Prim Dent J
December 2024
Ilser Turkyilmaz DMD, PhD Associate Dean of Digital Innovation, Professor and Chair, Department of Comprehensive Care, School of Dental Medicine, Case Western Reserve University, Cleveland, Ohio, USA.
Accurate working impression is an essential requirement for the fabrication of implant prosthesis, and digital impressions have recently become more popular. In this case report, a completely digital workflow is introduced for the fabrication of three single-unit screw-retained implant crowns on the posterior maxilla by a dental student, under supervision. This approach involved the use of an intraoral scanner to capture a digital impression of the three implants and their surrounding mucosa, the opposing arch, and occlusion.
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- The MOTION trial aimed to evaluate the effectiveness of vimseltinib in reducing tumors in patients with symptomatic tenosynovial giant cell tumor (TGCT) when surgery wasn’t an option.
- The results indicated that participants treated with vimseltinib showed significant tumor shrinkage (30% or more) and reported improvements in mobility, physical function, and overall health compared to those on a placebo.
- Vimseltinib presents a promising new treatment option for TGCT, offering benefits in tumor reduction and quality of life with manageable side effects.
Assessment of salivary and serum leptin in tobacco smokers and oral squamous cell carcinoma-A case-control study.
J Stomatol Oral Maxillofac Surg
October 2024
Department of Public Health Dentistry, Post Graduate Institute of Dental Sciences, PGIMS Campus, Pt BD Sharma University of Health Sciences, Rohtak 124001, India.
Objectives: Oral squamous cell carcinoma (OSCC) is the most common head and neck malignancy and tobacco-related cancers account for a significant portion of all oral cancers. Cancer patients often suffer from cachexia, which contributes significantly to mortality. Leptin is a protein released by adipocytes identified to play an important role in obesity and inflammation.
View Article and Find Full Text PDFRationale and design of the BeyeOMARKER study: prospective evaluation of blood- and eye-based biomarkers for early detection of Alzheimer's disease pathology in the eye clinic.
Alzheimers Res Ther
August 2024
Amsterdam Neuroscience, Neurodegeneration, Amsterdam, 1081 HV, The Netherlands.
Background: Alzheimer's disease (AD) is a common, complex and multifactorial disease that may require screening across multiple routes of referral to enable early detection and subsequent future implementation of tailored interventions. Blood- and eye-based biomarkers show promise as low-cost, scalable and patient-friendly tools for early AD detection given their ability to provide information on AD pathophysiological changes and manifestations in the retina, respectively. Eye clinics provide an intriguing real-world proof-of-concept setting to evaluate the performance of these potential AD screening tools given the intricate connections between the eye and brain, presumed enrichment for AD pathology in the aging population with eye disorders, and the potential for an accelerated diagnostic pathway for under-recognized patient groups.
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