We discuss the diagnosis and the management of endometrial carcinoma in a single horn of bicornuate uterus in a 64-year-old woman as a case report. The case underwent laparoscopic radical hysterectomy and bilateral iliac lymphadenectomy. The gross examination of the uterus revealed a bicornuate uterus with a greater horn of 12 × 9 × 8 cm and a smaller horn of 10 × 3 cm. The cavity of the greater horn showed a neoplastic growth of 10 cm with infiltration of about 1,8 cm of the myometrium from whole thickness of 1.9 cm. while the other horn was free of tumor tissue. The microscopic examination of the uterus revealed G2 endometrioid adenocarcinoma of the endometrium of the greater horn with infiltration of more than 50% of the myometrium. In the presence of bicornuate uterus, a bilateral endometrial biopsy should be performed in order to reduce the risk of delayed or missed diagnosis. The management of a case of bicornuate unicollis uterus with endometrial carcinoma in only one horn is the same as patients with endometrial cancer in single uterus and depends mainly on stage and histological grade of the tumor. The possibility of existence of a separate uterine cavity should always be considered when endometrial cancer is clinically suspected but pathology fails to confirm the diagnosis. This points out the importance of a careful physical examination and radiographic evaluation in such cases.
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http://dx.doi.org/10.1016/j.jnci.2018.04.003 | DOI Listing |
Cureus
November 2024
Medicine, Gulf Medical University, Ajman, ARE.
A defect in the fusion of Müllerian ducts results in the uterine malformation of the bicornuate uterus. The bicornuate uterus is an uncommon condition, and it is associated with adverse early pregnancy and antenatal events, such as recurrent miscarriages, preterm labor, and delivery. The bicornuate uterus has two symmetric uterine cavities that are fused caudally and have some degree of communication between the two cavities, usually at the uterine isthmus.
View Article and Find Full Text PDFJCEM Case Rep
January 2025
Department of Pediatrics, Division of Pediatric Endocrinology, Yale School of Medicine, New Haven, CT 06510, USA.
46,XY sex reversal 11 (SRXY11) is a rare and recently identified form of 46,XY difference in sexual development (DSD), caused by variants in the DEAH-Box Helicase 37 gene (). is crucial for ribosome biogenesis, but its specific role in gonadal development remains unclear. The genital phenotype varies widely, ranging from typical female to typical male.
View Article and Find Full Text PDFAn 11-year-old postmenarchal female presented to the pediatric emergency department (ED) with 2 days of periumbilical and right lower abdominal pain. Radiology-performed ultrasound (RADUS) did not visualize the appendix, and there was a plan for surgical consultation to decide between serial abdominal exams versus computed tomography (CT) scan. While awaiting consultation and to help further narrow the differential diagnosis, the emergency provider performed a point of care ultrasound (POCUS) of the urinary tract.
View Article and Find Full Text PDFCureus
October 2024
Pediatric Surgery, Government Medical College, Kozhikode, Kozhikode, IND.
Female hypospadias is an extremely rare condition characterised by urethral meatus placed within the introitus on the anterior vaginal wall, along with foreshortening of the urethra. It is an often missed anomaly that usually co-exists with other genitourinary conditions like ectopic ureter, renal anomalies, septate vagina and bicornuate uterus. A case series of five girls who had hypospadias is being described.
View Article and Find Full Text PDFJ Family Reprod Health
September 2024
Department of Obstetrics & Gynecology, Vydehi Institute of Medical Sciences & Research Center, Bangalore, Karnataka, India.
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