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A Rare Case of Familial Methemoglobinemia with Congenital Heart Disease.
Oman Med J
May 2024
Department of Medical Oncology and Hematology, All India Institute of Medical Sciences, Uttarakhand, India.
Methemoglobinemia is a rare dyshemoglobin disorder which can either be congenital or acquired. Dyshemoglobin disorders can be asymptomatic or symptomatic. We narrate the case of a 12-year-old girl who presented with a fever, cough, and oxygen saturation of 85%.
View Article and Find Full Text PDFThe first Chinese with Hb Chile leading to chronic anemia and methemoglobinemia: a case report.
BMC Pediatr
December 2023
Department of Pediatrics, the Affiliated Hospital of Southwest Medical University, Luzhou, China.
Background: Hemoglobin (Hb) Chile [β28(B10) Leu > Met; HBB: c.85 C > A] is a rare hemoglobin variant caused by a missense mutation in the HBB gene. Only one case of Hb Chile has been reported worldwide so far.
View Article and Find Full Text PDFPhenazopyridine-Induced Methemoglobinemia in a Jehovah's Witness Treated with High-Dose Ascorbic Acid Due to Methylene Blue Contradictions: A Case Report and Review of the Literature.
Hematol Rep
May 2023
Department of Internal Medicine, Indiana University School of Medicine-Muncie, Muncie, IN 47306, USA.
Methemoglobinemia is an acute medical emergency that requires prompt correction. Physicians should have a high degree of suspicion of methemoglobinemia in cases that present with hypoxemia that does not resolve with supplemental oxygenation, and they should confirm this suspicion with a positive methemoglobin concentration on arterial blood gas. There are multiple medications that can induce methemoglobinemia, such as local anesthetics, antimalarials, and dapsone.
View Article and Find Full Text PDFTrimethoprim/sulfamethoxazole-induced methemoglobinemia in pediatric patient: A case report.
Clin Case Rep
March 2023
Pharmacy Services Administration King Saud Medical City, Riyadh First Cluster, MOH Riyadh Saudi Arabia.
In this report, a case of high dose of sulfamethoxazole/trimethoprim-induced methemoglobinemia and is reported in a young boy with ventilator-associated pneumonia and was treated successfully with methylene blue and cessation of the offending agent.
View Article and Find Full Text PDFFavism: Clinical Features at Different Ages.
Nutrients
January 2023
Laboratory of Dietetics and Clinical Nutrition, Department of Public Health, Experimental and Forensic Medicine, University of Pavia, Via Bassi 21, 27100 Pavia, Italy.
Favism is a hemolytic disease due to the ingestion of fava beans in individuals with glucose-6-phosphate dehydrogenase (G6PD) deficiency. There is wide inter- and intra-individual variability in the development of hemolytic crisis, and several factors influence it: quantity, quality, ripeness of fava beans, and age of onset. In this narrative review of case reports and case series, we reported the predisposing factors and clinical features for four different age groups classified as follows: pregnant women and infants (i.
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