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http://dx.doi.org/10.1136/vr.k1965 | DOI Listing |
Sci Total Environ
January 2025
Université Paris Cité and Univ Paris Est Creteil, CNRS, LISA, F-75013 Paris, France.
Understanding the solubility dynamics of elements during wet deposition is crucial for assessing their environmental impacts. In this study, we investigated the solubility behaviour of various elements originating from natural and anthropogenic sources using a dataset of 106 samples describing the sequential collections of 8 rainfall events. Our results reveal distinct solubility patterns depending on the type of event, with mineral-dust events exhibiting lower solubility and anthropogenic events displaying higher solubility, in relation with dust content and pH.
View Article and Find Full Text PDFMath Biosci Eng
December 2024
Department of Mathematics, New Mexico Tech, New Mexico 87801, USA.
We present a modeling strategy to forecast the incidence rate of dengue in the department of Córdoba, Colombia, thereby considering the effect of climate variables. A Seasonal Autoregressive Integrated Moving Average model with exogenous variables (SARIMAX) model is fitted under a cross-validation approach, and we examine the effect of the exogenous variables on the performance of the model. This study uses data of dengue cases, precipitation, and relative humidity reported from years 2007 to 2021.
View Article and Find Full Text PDFNat Genet
January 2025
Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Members of the KMT2C/D-KDM6A complex are recurrently mutated in urothelial carcinoma and in histologically normal urothelium. Here, using genetically engineered mouse models, we demonstrate that Kmt2c/d knockout in the urothelium led to impaired differentiation, augmented responses to growth and inflammatory stimuli and sensitization to oncogenic transformation by carcinogen and oncogenes. Mechanistically, KMT2D localized to active enhancers and CpG-poor promoters that preferentially regulate the urothelial lineage program and Kmt2c/d knockout led to diminished H3K4me1, H3K27ac and nascent RNA transcription at these sites, which leads to impaired differentiation.
View Article and Find Full Text PDFZ Naturforsch C J Biosci
January 2025
Department of Biotechnology, 502852 School of Life Science and Biotechnology, Adamas University, Barasat, Kolkata 700126, India.
Drought stress remains a serious concern in L. var , cultivar Satabdi (IET4786) production, particularly during the earliest growth phases, ultimately affecting yield due to the recent trend of delayed rain arrival in West Bengal, India. This study aimed to develop a cost-effective strategy to improve the drought tolerance capacity of rice seedlings by priming the seeds with flavonoid-enriched extract (FEE) of French marigold () petals to withstand the initial drought milieu.
View Article and Find Full Text PDFEnviron Pollut
January 2025
Cawthron Institute, 98 Halifax Street East, Nelson, 7010, New Zealand.
Global declines in wild mussel populations and production have been linked to the impacts of climate change and pollution. Summer die-offs of mussels (Perna canaliculus), spat retention issues, and a severe decline in mussel spat settlement have been reported in the Marlborough Sounds, an important area for mussel farming in New Zealand. Preliminary evidence suggests that naturally occurring contaminants and changing land use in the surrounding areas, could contribute to the decline of this species.
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