The ubiquitin-proteasome system controls the stability of myriad protein substrates via short sequence motifs called degrons. Studies by Koren et al. (2018) and Lin et al. (2018) have uncovered a broad new class of degrons located at the extreme C terminus of substrates.
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| http://dx.doi.org/10.1016/j.molcel.2018.05.006 | DOI Listing |
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