Objective: To compare the automatic potentiometry and oxidation-reduction titration methods in determining easily oxidized substances in infusion sets for single use.
Methods: The easily oxidized substances in infusion sets for single use were determined using two methods. The precise test and the Student's test were be carried out.
Results: Both of the methods could satisfy the analytic demand. The relative standard deviation of automatic potentiometry is 0.06%; the relative standard deviation of oxidation-reduction titration method is 0.07%; when α was 0.05, P value was 0.92. There was no statistically significant difference between the two methods.
Conclusion: Automatic potentiometry method can substitute oxidation-reduction titration methods.
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Anal Chim Acta
September 2021
Biosensor National Special Laboratory, Key Laboratory for Biomedical Engineering of Ministry of Education, Department of Biomedical Engineering, Zhejiang University, Hangzhou, 310027, China. Electronic address:
Light-addressable potentiometric sensor (LAPS) has been widely used in biomedical applications since its advent. As a member of the potentiometric sensors, ion-sensitive LAPS (ISLAPS) can be obtained by modifying ion selective sensing membrane on the sensor surface. Compared with the conventional ion-selective electrodes (ISEs) with liquid contact, the all-solid-state ISEs have more advantages such as easy maintenance, more convenient for miniaturization and practical applications.
View Article and Find Full Text PDFAnn Biol Clin (Paris)
August 2021
Service de biochimie et génétique moléculaire, CHU Clermont-Ferrand, France.
Natremia is an important biological parameter providing information on the hydration state of patient's intracellular sector. Its measurement can be carried out either by multiparametric laboratory analyser (indirect potentiometry) or delocalized biology analyser (direct potentiometry). The main problem is that for a same patient, these two analysers can give quite different results, hence inducing interpretation problems for clinician.
View Article and Find Full Text PDFBiosensors (Basel)
February 2021
Chemistry Department, Shiraz University, Shiraz 71454, Iran.
An origami three-dimensional design of a paper-based potentiometric sensor is described. In its simplest form, this electrochemical paper-based analytical device (ePAD) is made from three small parts of the paper. Paper layers are folded on each other for the integration of a solid contact ion selective electrode (here a carbon-paste composite electrode) and a solid-state pseudo-reference electrode (here writing pencil 6B on the paper), which are in contact with a hydrophilic channel fabricated on the middle part (third part) of the paper.
View Article and Find Full Text PDFJ Neuroeng Rehabil
August 2020
Bioinspired VLSI Circuits and Systems Group, Department of Bioengineering, Imperial College London, Exhibition Road, London, SW7 2AZ, UK.
Background: Traumatic Brain Injury (TBI) is a leading cause of fatality and disability worldwide, partly due to the occurrence of secondary injury and late interventions. Correct diagnosis and timely monitoring ensure effective medical intervention aimed at improving clinical outcome. However, due to the limitations in size and cost of current ambulatory bioinstruments, they cannot be used to monitor patients who may still be at risk of secondary injury outside the ICU.
View Article and Find Full Text PDFArtif Organs
October 2019
Fresenius Medical Care Deutschland GmbH, Bad Homburg, Germany.
In standard care, hemodialysis patients are often treated with a center-specific fixed dialysate sodium concentration, potentially resulting in diffusive sodium changes for patients with plasma sodium concentrations below or above this level. While diffusive sodium load may be associated with thirst and higher interdialytic weight gain, excessive diffusive sodium removal may cause intradialytic symptoms. In contrast, the new hemodialysis machine option "Na control" provides automated individualization of dialysate sodium during treatment with the aim to reduce such intradialytic sodium changes without the need to determine the plasma sodium concentration.
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