We retrospectively assessed breakthrough invasive fungal infections (b-IFIs) in 100 consecutive patients with leukemia receiving single-agent isavuconazole; 13 had documented b-IFIs (candidiasis in 6, mucormycosis in 4). All b-IFIs were observed in patients with prolonged neutropenia and active leukemia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454429PMC
http://dx.doi.org/10.1093/cid/ciy406DOI Listing

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