The effect of antiretroviral therapy (ART) on chloroquine and desethyl-chloroquine plasma concentrations was evaluated in clinical trial participants. Concentrations did not differ among participants receiving protease inhibitor-based ART (n = 9), efavirenz-based ART (n = 15), or other ART (n = 8) and those not receiving ART (n = 31). Efavirenz seemed to inhibit chloroquine desethylation.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206114 | PMC |
| http://dx.doi.org/10.1093/cid/ciy405 | DOI Listing |
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