Aim: Current attempts to modulate the human microbiota and immune responses are based on probiotics or human-derived bacterial transplants. We investigated microbial modulation by soil and plant-based material.
Materials & Methods: We performed a pilot study in which healthy adults were exposed to the varied microbial community of a soil- and plant-based material.
Results: The method was safe and feasible; exposure was associated with an increase in gut microbial diversity.
Conclusion: If these findings are reproduced in larger studies nature-derived microbial exposure strategies could be further developed for testing their efficacy in the treatment and prevention of immune-mediated diseases.
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| http://dx.doi.org/10.2217/fmb-2017-0286 | DOI Listing |
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