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Association between intraoperative fluid management and postoperative outcomes in living kidney donors: a retrospective cohort study.

Sci Rep

January 2025

Department of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81, Irwon-ro, Gangnam-gu, Seoul, 06351, Republic of Korea.

Optimal fluid strategy for laparoscopic donor nephrectomy (LDN) remains unclear. LDN has been a domain for liberal fluid management to ensure graft perfusion, but this can result in adverse outcomes due to fluid overload. We compared postoperative outcome of living kidney donors according to the intraoperative fluid management.

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Following severe burns, the predominant concern is significant fluid loss, for which balanced crystalloid solutions are widely recommended as the primary intravenous resuscitation fluids. However, current literature lacks a clear distinction among various buffered crystalloid types that might be most effective in the early resuscitation of burn patients. This retrospective study was conducted to identify the optimal resuscitation fluid for major burns and to assess the clinical outcomes associated with isotonic crystalloid solutions compared to hypotonic crystalloids, specifically in terms of urinary output, acid-base balance, and electrolyte stability.

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Background: Some studies suggest that balanced solutions may improve outcomes in critical care patients. However, in patients with traumatic brain injury (TBI) existing data indicate that normal saline may be preferred. We hypothesized that mortality in critically ill patients with and without TBI would differ with the use of balanced salt solutions versus normal saline.

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Volume kinetic analysis of 2 crystalloid fluid bolus rates in anesthetized cats.

J Vet Emerg Crit Care (San Antonio)

January 2025

J. T. Vaughan Large Animal Teaching Hospital, Auburn University, Auburn, Alabama, USA.

Objective: To investigate the volume kinetic between 2 crystalloid fluid bolus rates in anesthetized cats.

Design: Prospective, randomized, dose-response study.

Setting: University laboratory.

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