The immune status was investigated in 32 patients with acute hepatitis of mixed etiology and in 39 HBsAg carriers, superinfected with delta virus. The relationship of changes in the immune status with a course and outcomes of acute delta virus infection was revealed. These changes returned to normal on patients with a cyclic course of disease, persisted in patients with a lingering process, and progressed in the development of subacute liver dystrophy. The most noticeable shifts (a decrease in all indices of the immune system) were revealed in patients with a fulminant course of disease.
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