The genomic medicine model: an integrated approach to implementation of family health history in primary care.

Per Med

Duke Center for Personalized Medicine & Duke Institute for Genome Sciences & Policy, 3475 Erwin Road, Wallace Clinic Ste 204, Durham, NC 27705, USA.

Published: May 2013

As an essential tool for risk stratification, family health history (FHH) is a central component of personalized medicine; yet, despite its widespread acceptance among professional societies and its established place in the medical interview, its widespread adoption is hindered by three major barriers: quality of FHH collection, risk stratification capabilities and interpretation of risk stratification for clinical care. To overcome these barriers and bring FHH to the forefront of the personalized medicine effort, we developed the genomic medicine model (GMM) for primary care. The GMM, founded upon the principles of the Health Belief Model, Adult Learning Theory and the implementation sciences, shifts responsibility for FHH onto the patient, uses information technology (MeTree) for risk stratification and interpretation, and provides education across multiple levels for each stakeholder, freeing up the clinical encounter for discussion around personalized preventive healthcare plans. The GMM has been implemented and optimized as part of an implementation-effectiveness hybrid pilot study for breast/ovarian cancer, colon cancer and thrombosis, and risk for hereditary cancer syndromes in two primary care clinics in NC, USA. This paper describes the conceptual development of the model and key findings relevant for broader uptake and sustainability in the primary care community.

Download full-text PDF

Source
http://dx.doi.org/10.2217/pme.13.20DOI Listing

Publication Analysis

Top Keywords

primary care
16
risk stratification
16
genomic medicine
8
medicine model
8
family health
8
health history
8
personalized medicine
8
care
5
risk
5
model
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!