Two kinds of matrices of genetic distances were compared. The first originate from the distribution of surnames frequencies in communities of some districts of Kostroma province. The others were constructed, based on the population size and the physical distances between populations. Essential similarity in results obtained by these two methods was noted. The differences arise, due to the elements of infrastructure in the real populations which are not taken into account using the second method.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Ophthalmo-genetic analysis of Pakistani patients with nonsyndromic oculocutaneous albinism through whole exome sequencing.
J Pak Med Assoc
May 2017
Gomal Centre of Biochemistry and Biotechnology, Gomal University, Dera Ismail Khan, KPK, Pakistan.
Oculocutaneous albinism (OCA) is a disorder of defective melanin biosynthesis that is characterized by hypo-pigmentation of skin, hair and retinal pigment epithelium. Phenotypically, OCA patients exhibit white milky skin, whitish to golden hair and deterioration of retinal cells. Until recently, genetic studies have reported seven causative genes (TYR, TYRP1, OCA2, SLC45A2, SLC24A2, C10ORF11 and MCIR) and an uncharacterized OCA5 locus.
View Article and Find Full Text PDF[On the possibility to determine genetic identity of the tissues with malignant tumours imbedded in paraffin blocks].
Sud Med Ekspert
September 2016
B.V. Petrovsky Russian Research Centre of Surgery,Moscow, Russia, 119991.
The results of analysis of the literature data were used to develop the forensic medical criteria for the assessment of the suitability of paraffin blocks containing the imbedded malignant tumours for the genetic identification of the tissues. The forensic medical criteria and the algorithm for the preliminary characteristic of the material of interest were proposed to avoid the potential errors. It is not recommended to use gastrointestinal carcinomas, breast tumours, and poorly differentiated ovarian tumours.
View Article and Find Full Text PDFHeparin traditionally used as an anticoagulant for blood preparations is one of the most powerful inhibitors of the polymerase chain reaction. The molecular genetic analysis for the purpose of forensic medical expertise encounters difficulties when DNA preparations obtained from heparinized samples have to be used. In our practical work, we were faced with the necessity to use heparin-treated blood samples.
View Article and Find Full Text PDF[Li-Fraumeni syndrome: clinico-molecular diagnostics and medico-genetic counseling].
Vestn Ross Akad Med Nauk
April 2012
Li-Fraumeni syndrome (sarcoma family syndrome, OMIM 151623) is a rare clinically and genetically hetergoeneous autosomal dominant disorder characterized by the evolvement and accumulation of soft-tissue osteogenic sarcomas in members of a family, as well as uni- and bilateral breast cancer in young women, brain tumours, adrenocortical cancer, and lymphoproliferative diseases. Germinal mutations of the TP53 gene constitute the etiological genetic basis of Li-Fraumeni syndrome. American Society of Clinical Oncology (ASCO) and National Comprehensive Cancer Network developed recommendations for genetic testing and observation of carriers of TP53 mutations.
View Article and Find Full Text PDFDigital images of the iris were received for study peculiarities of the iris color during the anthropological examination of 578 students aged 16-24 years. Simultaneously with the registration of the digital images, the visual assessment of the eye color was carried out using the traditional scale of Bunak, based on 12 ocular prostheses. Original software for automatic determination of the iris color based on 12 classes scale of Bunak was designed, and computer version of that scale was developed.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!