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NPAS3 exonic SNP genotype is linked to working memory performance in healthy young adults.
Psychiatry Res
July 2018
Department of Psychiatry, University of Alberta, Edmonton, AB, Canada; Neuropsychology Service, Alberta Hospital Edmonton, Edmonton, AB, Canada. Electronic address:
Cross-disorder analysis of bipolar risk genes: further evidence of DGKH as a risk gene for bipolar disorder, but also unipolar depression and adult ADHD.
Neuropsychopharmacology
September 2011
Department of Psychiatry, Psychosomatics and Psychotherapy, Psychiatric Neurobiology and Bipolar Disorder Program, University of Würzburg, Würzburg, Germany.
Recently, several genome-wide association studies (GWAS) on bipolar disorder (BPD) suggested novel risk genes. However, only few of them were followed up and further, the specificity of these genes is even more elusive. To address these issues, we genotyped SNPs in ANK3, CACNA1C, CMTM8, DGKH, EGFR, and NPAS3, which were significantly associated with BPD in previous GWAS, in a sample of 380 BPD patients.
View Article and Find Full Text PDFAssociation of NPAS3 exonic variation with schizophrenia.
Schizophr Res
July 2010
Department of Medical Genetics, University of Alberta, Edmonton, Alberta, Canada.
Background: We previously identified the neuronal PAS3 (NPAS3) gene as a candidate gene for schizophrenia. A mother and daughter, both with schizophrenia, were carriers of a translocation, t(9;14)(q34;q13), that disrupts the NPAS3 gene. The gene is located at 14q13, a region implicated in schizophrenia and bipolar disorder in various linkage studies.
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