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Characterization of the Metabolic Proteome of Serum From Patients With Diabetic Distal Symmetric Polyneuropathy.
Proteomics Clin Appl
November 2024
Department of Endocrinology and Metabolism, Huashan Hospital, Fudan University, Shanghai, China.
Aims: The pathophysiological of diabetic distal symmetric polyneuropathy (DSPN) remains to be elucidated and there are no diagnostic or prognostic biomarkers for the condition. In this explorative proteomic study, metabolic proteome profiling of serum in patients with/without DSPN was analyzed. We aimed to discover proteins with different abundance ranges through proximity extension assay (PEA) technology.
View Article and Find Full Text PDFWhat's the Impact of Safety Footwear on Workers Concerning Foot-Related Problems? A Systematic Review.
Healthcare (Basel)
July 2024
1st Orthopaedics and Traumatologic Clinic, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.
Article Synopsis
- - The study evaluated how safety footwear (SF) affects workers’ foot health, focusing on issues like foot pain, discomfort, and skin lesions.
- - A systematic search through major medical databases found 7 relevant studies, revealing a high prevalence of discomfort (42.3% to 60.8%) and common foot problems such as Irritant Contact Dermatitis (97.9%).
- - Recommendations for improving SF design include selecting appropriate styles for specific job tasks, ensuring breathable materials, focusing on fit, and providing education on footwear use.
What's new in pediatric lower limb reconstruction?
J Child Orthop
August 2024
Paediatric Orthopaedics, Deformity Reconstruction and Foot Surgery, Muenster University Hospital, Muenster, Germany.
The last years brought many advances relevant to lower limb reconstruction. It feels like guided growth has been looked at from every angle, and still there are new emerging concepts like rotational guided growth waiting to be validated. New hexapod external devices are more accurate and easier to use, and new unilateral fixators allow for more versatile and stable fixation and lengthening.
View Article and Find Full Text PDFWhat's New in Foot and Ankle Surgery.
J Bone Joint Surg Am
May 2024
Department of Orthopaedic Surgery, MedStar Union Memorial Hospital, Baltimore, Maryland.
What's the evidence on surgical treatment for congenital brachymetatarsia: A systematic review and meta-analysis.
J Orthop
March 2024
1st Orthopaedics and Traumatologic Clinic, IRCCS Istituto Ortopedico Rizzoli, 40136, Bologna, Italy.
Purpose: Brachymetatarsia is marked by the shortened length of one or more metatarsal bones. Several operative options have been suggested without demonstrating the superiority of one treatment over another. This study aims to assess the main available treatment, bone lengthening achieved, clinical outcomes, and complications pertaining to congenital brachymetatarsia interventions.
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