Short genome report of cellulose-producing commensal 1094.

Stand Genomic Sci

1Département de Microbiologie, Unité de Génétique des Biofilms, Institut Pasteur, 25-28 rue du Dr. Roux, F-75015 Paris, France.

Published: May 2018

AI Article Synopsis

  • Bacterial surface colonization and biofilm formation depend on an extracellular polymeric matrix, often made up of cellulose, which helps cells stick to each other and surfaces.
  • Researchers sequenced the complete genome of a cellulose-producing strain called 1094 and compared it to five related strains in phylogenetic group A.
  • The study includes an analysis of genes responsible for cellulose biosynthesis and explores reasons why some strains may have lost this crucial ability.

Article Abstract

Bacterial surface colonization and biofilm formation often rely on the production of an extracellular polymeric matrix that mediates cell-cell and cell-surface contacts. In and many and cellulose is often the main component of the extracellular matrix. Here we report the complete genome sequence of the cellulose producing strain 1094 and compare it with five other closely related genomes within phylogenetic group A. We present a comparative analysis of the regions encoding genes responsible for cellulose biosynthesis and discuss the changes that could have led to the loss of this important adaptive advantage in several strains. Data deposition: The annotated genome sequence has been deposited at the European Nucleotide Archive under the accession number PRJEB21000.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944007PMC
http://dx.doi.org/10.1186/s40793-018-0316-0DOI Listing

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