AI Article Synopsis
- A novel pyrene-based fluorescent probe, HPTS-DNP, was developed for highly sensitive and visual detection of thiophenol in water.
- The detection relies on a chemical reaction that transforms HPTS-DNP into a more fluorescent compound, HPTS, which allows for quick and efficient measurement with very low background interference.
- This method demonstrates excellent selectivity, precision, and accuracy, making it suitable for environmental monitoring and potential applications in bioimaging.
Article Abstract
We report a simple pyrene-based fluorescent probe, sodium 8-(2,4-dinitrophenoxy)pyrene-1,3,6-trisulfonate (HPTS-DNP), for the ultrasensitive and visual detection of thiophenol in 100% aqueous media. The sensing mechanism of this method is based on nucleophilic aromatic substitution on HPTS-DNP caused by thiophenol to afford a highly fluorescent product, 8-hydroxypyrene-1,3,6-trisulfonic acid trisodium salt (HPTS). The extremely low fluorescence background of HPTS-DNP and high quantum yield of HPTS ensure the superior sensing performance toward thiophenol, including rapid responses, off-on detection mode and excellent sensitivity. The detection limit is as low as 0.49 nmol L according to the measurements with a spectrofluorimeter. This probe also features good selectivity (response ratio of thiophenol to interferents >30), precision (2.93%) and accuracy (102%). This approach could be applied for monitoring the thiophenol concentrations in environmental water samples. HPTS-DNP also showed good cell permeation capacity and low cellular cytotoxicity, indicating further application in bioimaging studies.
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| http://dx.doi.org/10.1016/j.talanta.2018.03.068 | DOI Listing |
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