Four new C-diterpenoid alkaloids, rotundifosines D-G (), along with eight known ones () were isolated from the whole plant of Kar. & Kir. The structures of the compounds were elucidated on the basis of spectroscopic analyses, including HR-ESI-MS and 1D, 2D NMR. Rotundifosine F () is a rare C-diterpenoid alkaloid with quaternary ammonium salt. Alkaloids , , , , and were evaluated for cytotoxicity against MCF-7, HCT-116 and HepG2 human cancer cell lines.
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http://dx.doi.org/10.1080/10286020.2018.1473384 | DOI Listing |
J Asian Nat Prod Res
July 2019
a School of Life Science and Engineering , Southwest Jiaotong University, Chengdu 610031 , China.
Four new C-diterpenoid alkaloids, rotundifosines D-G (), along with eight known ones () were isolated from the whole plant of Kar. & Kir. The structures of the compounds were elucidated on the basis of spectroscopic analyses, including HR-ESI-MS and 1D, 2D NMR.
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