Small bowel obstruction is a common and significant surgical presentation. Approximately 30% of presentations will require surgery during admission. The great challenge of adhesive small bowel obstruction (ASBO) management is the early detection of silent intestinal ischaemia in patients initially deemed suitable for conservative therapy. Recent literature emphasizes the effectiveness of computed tomography enterography and water-soluble contrast studies in the management of ASBO. Low-volume undiluted water-soluble contrast has been shown to have both triage and therapeutic value in the management of ASBO. Their use has been demonstrated to reduce the need for surgery to below 20%. There has also been growing interest in clinicoradiological algorithms which aim to predict ischaemia early in the course of presentation. The aim of this review is to summarize the latest evidence and clarify previous uncertainties, specifically regarding the duration of conservative treatment, timing of contrast studies and the reliability of predictive algorithms. Based on this latest evidence, we have formulated a management protocol which aims to integrate these latest developments and formalize a strategy for best management in ASBO.
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http://dx.doi.org/10.1111/ans.14556 | DOI Listing |
Front Endocrinol (Lausanne)
January 2025
Department of Metabolic Surgery, Jinshazhou Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.
Bariatric surgery is an effective treatment for type 2 Diabetes Mellitus (T2DM), yet the precise mechanisms underlying its effectiveness remain incompletely understood. While previous research has emphasized the role of rearrangement of the gastrointestinal anatomy, gaps persist regarding the specific impact on the gut microbiota and barriers within the biliopancreatic, alimentary, and common limbs. This study aimed to investigate the effects of duodenal-jejunal bypass (DJB) surgery on obese T2DM mice.
View Article and Find Full Text PDFInt J Parasitol Parasites Wildl
April 2025
División Zoología Invertebrados, Facultad de Ciencias Naturales y Museo, Universidad Nacional de La Plata, CONICET-Centro Científico Tecnológico La Plata, Buenos Aires. Paseo del Bosque s/n La Plata, (1900), Buenos Aires, Argentina.
Through morphological and molecular studies, the natural life cycle of Dollfus, 1960 (Cestoda: Taeniidae) from Argentine Patagonia is elucidated, involving subterranean rodents (Ctenomyidae) as intermediate hosts, and the Andean fox (Canidae) as definitive host. Metacestodes (mono- and polycephalic fimbriocerci) were found mainly in the peritoneal cavity of , and the strobilate adult in the intestine of . Correspondence between metacestodes and strobilate adults was based primarily on number, size and shape of rostellar hooks: 45-53 hooks alternated in two rows, small hooks 88-180 μm long and large hooks 230-280 μm long, with the characteristic shape described in the two main description of the species, both that of the metacestode (original description) and that of the strobilate adult (obtained experimentally).
View Article and Find Full Text PDFSurg Pract Sci
June 2022
University of Kentucky, Lexington, KY, USA.
Introduction: Colorectal surgery (CRS) patients are at high risk for venous thromboembolism (VTE). The Caprini model elucidates that comorbidities compound to increase VTE risk, but this association in CRS patients remains undefined. We hypothesize that the compounding presence of comorbidities in patients undergoing colorectal resection (CRR) or small bowel resection (SBR) is associated with greater postoperative VTE risk.
View Article and Find Full Text PDFSurg Pract Sci
June 2022
Department of Surgery, Division of Trauma and Acute Care Surgery, University of California, Davis, United States.
Background: The American Association for the Surgery of Trauma (AAST) grading system for intestinal obstruction may be a useful measure of anatomic severity, but its construct validity has not yet been evaluated in patients with either large or small bowel obstruction, using the grade applicable at initial presentation (rather than after definitive management).
Materials And Methods: We conducted a retrospective case series of adult inpatients presenting with intestinal obstruction at our center during 2008-2014. We excluded patients without confirmed intestinal obstruction, those with obstruction secondary to a hernia, those who were treated for >24 hours at another hospital, and those with a previous encounter already included in the study.
Front Cell Infect Microbiol
January 2025
Scientific Research Department, Hunan Academy of Chinese Medicine, Changsha, China.
Objective: This study aims to explore the therapeutic mechanism of Massa Medicata Fermentata (MMF) with different formulations on spleen deficiency constipation in mice by analyzing gastrointestinal hormones, D-xylose, intestinal microbiota, and intestinal enzyme activities.
Methods: A spleen deficiency constipation model was established using an oral administration of Sennae Folium decoction combined with controlled diet and water intake. After successful model establishment, the mice with spleen deficiency constipation were treated with MMF S1, S2, S3.
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