The Most Important Virulence Markers of and Their Role during Infection.

Genes (Basel)

Department of Epizootiology, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego 2 Str., 10-719 Olsztyn, Poland.

Published: May 2018

is the causative agent of yersiniosis, a zoonotic disease of growing epidemiological importance with significant consequences for public health. This pathogenic species has been intensively studied for many years. Six biotypes (1A, 1B, 2, 3, 4, 5) and more than 70 serotypes of have been identified to date. The biotypes of are divided according to their pathogenic properties: the non-pathogenic biotype 1A, weakly pathogenic biotypes 2⁻5, and the highly pathogenic biotype 1B. Due to the complex pathogenesis of yersiniosis, further research is needed to expand our knowledge of the molecular mechanisms involved in the infection process and the clinical course of the disease. Many factors, both plasmid and chromosomal, significantly influence these processes. The aim of this study was to present the most important virulence markers of and their role during infection.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5977175PMC
http://dx.doi.org/10.3390/genes9050235DOI Listing

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