The aim of the present work was to evaluate and compare variations in mineral density (MD) using laser-induced fluorescence (LF) after applying 5% Sodium Fluoride Varnish (Duraphat®), 5% Sodium Fluoride Varnish with Tricalcium Phosphate (Clinpro®) or Casein phosphopeptide-amorphous calcium phosphate (Recaldent®) on teeth with Molar Incisor Hypomineralization (MIH). Mineral density of 92 MIH teeth with mild (Mi) and moderate (Mo) lesions was assessed using a DIAGNOdent device (KaVo, Biberach, Germany). LF values were recorded on day 0 (baseline) and on days 15, 30 and 45; the remineralizing agents were applied immediately after LF readings at baseline and on days 15 and 30. Data corresponding to Mi and Mo lesions were analyzed separately. Significant differences were observed both in mild (p<0.01) and moderate (p<0.000005) lesions. Differences between Recaldent® and Clinpro®, and between Duraphat® and Clinpro® (global level 0.10) were found in Mi lesions. All 3 pairs ofproducts differed significantly in Mo lesions (global level 0.05). The results obtained under the conditions used here allow concluding that Clinpro® was more effective in mild lesions whereas Duraphat® was more effective in moderate lesions.
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