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Pharmacological pain management in patients with rheumatoid arthritis: a narrative literature review.
BMC Med
January 2025
Primary Care Centre Versus Arthritis, School of Medicine, Keele University, Keele, UK.
Background: Pain is a major challenge for patients with rheumatoid arthritis (RA), with many people suffering chronic pain. Current RA management guidelines focus on assessing and reducing disease activity using disease-modifying anti-rheumatic drugs (DMARDs). Consequently, pain care is often suboptimal, with growing evidence that analgesics are widely prescribed to patients with RA, despite potential toxicities and limited evidence for efficacy.
View Article and Find Full Text PDFHealth system financing fragmentation and maternal mortality transition in Mexico, 2000-2022.
Int J Equity Health
January 2025
Center for Health Systems Research, National Institute of Public Health, Cuernavaca, Morelos, Mexico.
Objective: To analyze the temporal and territorial relationship between health system financing fragmentation and maternal mortality in the last two decades in Mexico.
Methods: We conducted an ecological-longitudinal study of the maternal mortality ratio (MMR) in the 32 states of Mexico during the period 2000-2022. Annual MMRs were estimated at the national and state levels according to health insurance.
Academic Achievement, Externalizing Problems, and Close Friends in Middle School: Testing a Developmental Cascade Model Leading to Educational Attainment in the Late Twenties.
J Youth Adolesc
January 2025
Department of Psychology, George Mason University, Fairfax, VA, USA.
Because educational attainment is associated with well-being in the long term, it is important to understand the developmental processes that enhance academic outcomes during adolescence. Also, although the importance of friends is well documented in adolescence, little is known about how close friends' characteristics work together with youth's own characteristics to shape adolescents' educational trajectories. This study fills an important gap in knowledge by focusing on how middle school students' academic achievement and externalizing problems are associated with their friends' achievement and externalizing problems over time, and how these variables predict educational attainment in adulthood.
View Article and Find Full Text PDFExamining the human-centred challenges of human-swarm interaction.
Philos Trans A Math Phys Eng Sci
January 2025
Air Force Research Laboratory 711th Human Performance Wing, Wright-Patterson AFB, OH, USA.
We adopt a tripart approach in describing the human-centred challenges with human-swarm interaction. First, the results of large-N laboratory studies will be discussed which found evidence of trust biases (e.g.
View Article and Find Full Text PDFAn alternative approach to biokinetic modelling for phenol pollutant degradation and microbial growth using Genetic Programming.
Environ Technol
January 2025
Centre for Biotechnology, Kalasalingam Academy of Research and Education, Krishnankoil, India.
Biokinetic models can optimise pollutant degradation and enhance microbial growth processes, aiding to protect ecosystem protection. Traditional biokinetic approaches (such as Monod, Haldane, etc.) can be challenging, as they require detailed knowledge of the organism's metabolism and the ability to solve numerous kinetic differential equations based on the principles of micro, molecular biology and biochemistry (first engineering principles) which can lead to discrepancies between predicted and actual degradation rates.
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