Sporotrichin Skin Test for the Diagnosis of Sporotrichosis.

J Fungi (Basel)

Dermatology Service & Mycology Department, Hospital General de México, "Dr. Eduardo Liceaga", Balmis 148, Colonia Doctores, Ciudad de México 06726, Mexico.

Published: May 2018

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Article Abstract

Sporotrichosis is the most common implantation mycosis caused by several species of the complex. The gold standard for diagnosis is concerned with the isolation of the fungus; although, fresh examinations, staining, and biopsies are also helpful for this purpose. The sporotrichin is an antigenic complex comprised of a peptide-rhamnomannan, which is relevant with respect to pathogenic fungi; it is primarily used for serological and skin testing. We present a study regarding the use of sporotrichin as a diagnostic aid for cutaneous sporotrichosis. Furthermore, 138 cases with suspicion of sporotrichosis were included, 55 of which were proven through cultures. Moreover, out of these 55 cases, 52 (94.5%) tested positive for sporotrichin, while the negative cases corresponded to the disseminated cutaneous forms. We observed a sensitivity of 94.5% and a specificity of 95.2%. We consider that the use of sporotrichin as a skin test helps us as an auxiliary diagnosis before a positive sample culture.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023300PMC
http://dx.doi.org/10.3390/jof4020055DOI Listing

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