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Pathological and Molecular Characterization of Grass Carp Co-Infected with Two Species.
Animals (Basel)
January 2025
Key Laboratory of Freshwater Aquatic Genetic Resources, Ministry of Agriculture and Rural Affairs, Shanghai Ocean University, Shanghai 201306, China.
The grass carp () is highly susceptible to infections caused by species, particularly and . However, the immunological mechanisms underlying co-infection by these pathogens remain largely uncharted. This study investigated the pathogenesis and host immune response in grass carp following concurrent infection with and .
View Article and Find Full Text PDFMethyl 3-Bromo-4,5-dihydroxybenzoate Attenuates Inflammatory Bowel Disease by Regulating TLR/NF-κB Pathways.
Mar Drugs
January 2025
Biology Institute, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250103, China.
Inflammatory bowel disease (IBD) is characterized by uncontrolled, chronic relapsing inflammation in the gastrointestinal tract and has become a global healthcare problem. Here, we aimed to illustrate the anti-inflammatory activity and the underlying mechanism of methyl 3-bromo-4,5-dihydroxybenzoate (MBD), a compound derived from marine organisms, especially in IBD, using a zebrafish model. The results indicated that MBD could inhibit the inflammatory responses induced by CuSO, tail amputation and LPS in zebrafish.
View Article and Find Full Text PDFNeng-Jing-Huo Essential Oil Blend Inhibits Lipopolysaccharide-Induced Intracellular Reactive Oxygen Species Accumulation, Inflammation, and Apoptosis in Renal Tubular Epithelial Cells.
J Physiol Investig
January 2025
Department of Medical Laboratory and Biotechnology, Chung Shan Medical University, Taichung, Taiwan.
Acute kidney injury (AKI) is a common serious complication of sepsis that is characterized by the rapid deterioration of kidney function. Neng-Jing-Huo (NJH) is an essential oil blend, including Gaultheria procumbens, Zingiber officinale, Bulnesia sarmientoi, Artemisia vulgaris, and Styrax benzoin oils, with antimicrobial, antioxidant, and anti-inflammatory activities. Here, we investigated the effects of NJH on oxidative stress, inflammatory response, and apoptosis in an in vitro septic AKI model and explored the underlying mechanisms.
View Article and Find Full Text PDFBioactive arabinoxylan oligomers via colonic fermentation and enzymatic catalysis: Evidence of interaction with toll-like receptors from in vitro, in silico and functional analysis.
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March 2025
School of Science and Technology, Örebro University, 701 82 Örebro, Sweden. Electronic address:
Dietary fibers (DF) from plant-based foods promote health benefits through their physicochemical properties and fermentation by the gut microbiota, often studied in relation to changes in gut microbiota profile and production of gut microbiota-derived metabolites. Here, we characterized structural motifs (i.e.
View Article and Find Full Text PDFLow-Frequency Cyclic Stretch Upregulates the Expression of Nuclear Factor Erythroid 2-Related Factor 2 in Human Nucleus Pulposus Cells to Inhibit the Resistin-Induced Interleukin-20 Expression.
JOR Spine
March 2025
Department of Orthopedics, National Cheng Kung University Hospital, College of Medicine National Cheng Kung University Tainan Taiwan.
Background: Resistin may connect obesity and intervertebral disc (IVD) degeneration (IDD) and is linked with chronic inflammation. Furthermore, human IDD is characterized by high expression of interleukin-20 (IL-20). The response of human nucleus pulposus (NP) cells to tensile forces depends on both the duration and magnitude of the force applied.
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