Chitosan based metallic nanocomposite scaffolds as antimicrobial wound dressings.

Bioact Mater

Centre for Nanosciences and Molecular Medicine, Amrita Institute of Medical Sciences and Research Center, Amrita Vishwa Vidyapeetham, Kochi, 682 041, India.

Published: September 2018

Chitosan based nanocomposite scaffolds have attracted wider applications in medicine, in the area of drug delivery, tissue engineering and wound healing. Chitosan matrix incorporated with nanometallic components has immense potential in the area of wound dressings due to its antimicrobial properties. This review focuses on the different combinations of Chitosan metal nanocomposites such as Chitosan/nAg, Chitosan/nAu, Chitosan/nCu, Chitosan/nZnO and Chitosan/nTiO towards enhancement of healing or infection control with special reference to the antimicrobial mechanism of action and toxicity.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935789PMC
http://dx.doi.org/10.1016/j.bioactmat.2017.11.003DOI Listing

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