AI Article Synopsis
- Cardiovascular disease (CVD) is the top cause of death for women in the U.S., but atypical symptoms like nausea and fatigue complicate diagnosis.
- Current guidelines suggest exercise electrocardiography (ex-ECG) as the first test for women with suspected coronary artery disease (CAD), although its reliability is lower in females.
- Women often experience nonobstructive CAD and microvascular dysfunction, which impacts the accuracy of noninvasive diagnostic tests used to assess their cardiovascular health.
Article Abstract
Cardiovascular disease (CVD) is the leading cause of death in the United States, yet several factors make it challenging to diagnose in women. Although women have more frequent chest pain than men, atypical symptoms such as nausea, dyspnea, and fatigue make it difficult to determine their risk of coronary artery disease (CAD) before testing. Current guidelines recommend exercise electrocardiography (ex-ECG) as the initial test in symptomatic women with intermediate pretest probability who can exercise and have a normal resting ECG; however, treadmill ex-ECG testing has a significantly lower positive predictive value in women. In addition, women often have nonobstructive CAD in conjunction with microvascular dysfunction and other cardiovascular abnormalities that can decrease the accuracy of all noninvasive tests. The following provides an overview of exercise ECG, echocardiography, SPECT imaging, and various other available modalities and examines their effectiveness in diagnosing and managing symptomatic women with suspected CAD.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935278 | PMC |
| http://dx.doi.org/10.14797/mdcj-13-4-193 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Endovascular Thrombectomy for Extracranial Internal Carotid Artery Occlusions With Large Ischemic Strokes: Insights From the SELECT2 Trial.
Neurology
February 2025
Department of Neurology, Department of Stroke, University Hospital Cleveland Medical Center, Case Western Reserve University, Cleveland, OH.
Background And Objectives: Although previous trials have established the efficacy and safety of endovascular thrombectomy (EVT) in large ischemic core strokes, most of them excluded patients with extracranial internal carotid artery (e-ICA) occlusion. We aimed to compare outcomes in patients with e-ICA occlusion and large ischemic core infarcts treated with EVT vs medical management (MM).
Methods: This was a secondary analysis of the SELECT2 trial, a randomized controlled trial conducted at 31 international sites.
Factors associated with urinary incontinence in nulliparous female elite athletes: an exploratory, cross-sectional study using dynamic pelvic magnetic resonance imaging and questionnaire data.
J Urol
January 2025
Division of Urology, Department of Surgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.
Purpose: Urinary incontinence (UI) is common in nulliparous female elite athletes, but underlying pathophysiology is inadequately understood. We examined urinary symptoms and associated pelvic floor anatomy and function in this population, hypothesizing that athletes with UI would exhibit pelvic floor findings seen in older incontinent women (e.g.
View Article and Find Full Text PDFContemporary Insights into LMNA Cardiomyopathy.
Curr Cardiol Rep
January 2025
Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Purpose Of Review: This review aims to explore how a diagnosis of LMNA-related cardiomyopathy (LMNA-CM) informs clinical management, focusing on the prevention and management of its complications, through practical clinical strategies.
Recent Findings: Longitudinal studies have enhanced our understanding of the natural history of LMNA-CM including its arrhythmic and non-arrhythmic complications. A LMNA specific ventricular arrhythmia risk prediction strategy has been integrated into clinical practice guidelines.
Impact of Right Atrial Plication on Pulmonary Function and Heart Failure Symptoms: A Case Report.
Cureus
December 2024
Cardiovascular Surgery, IMS Katsushika Heart Center, Tokyo, JPN.
An 85-year-old woman with long-standing atrial fibrillation and severe tricuspid regurgitation presented with worsening symptoms and massive right atrial enlargement (RAE). The patient experienced shortness of breath even during minimal exertion, such as walking within her house, which significantly impacted her daily activities. Surgical intervention, including tricuspid valve replacement and right atrial plication (RAP), led to significant symptomatic relief and improved pulmonary function.
View Article and Find Full Text PDFUrinary Tract Infections (UTIs) in pregnant women can lead to pyelonephritis and preterm birth. We assessed UTI prevalence, etiology, antimicrobial resistance, and associated risk factors among pregnant women receiving antenatal care in rural Amhara, Ethiopia. 604 pregnant women were screened for UTI at ≤ 24 weeks gestational age from August 2020 to June 2022.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!