AI Article Synopsis
- A 76-year-old woman developed a rare liver abscess caused by Clostridium haemolyticum after undergoing transarterial chemoembolization (TACE) for hepatocellular carcinoma, presenting with abdominal pain and fever.
- Diagnosis was confirmed through a CT scan showing an air-filled abscess, with pus cultures identifying the Clostridium infection.
- Despite treatment with broad-spectrum antibiotics and drainage, the patient experienced a rapid decline in health, leading to her transfer for palliative care, highlighting the seriousness of Clostridium infections post-TACE.
Article Abstract
Rationale: Liver abscesses caused by Clostridium species infection are extremely rare.
Patient Concerns: The authors report the first case of a liver abscess due to Clostridium haemolyticum, which occurred after transarterial chemoembolization (TACE) for hepatocellular carcinoma, in a 76-year-old woman who presented with right upper quadrant pain and fever.
Diagnoses: Computed tomography of the abdomen after the second TACE showed an air-filled abscess around a compact, lipiodolized lesion in the right hepatic lobe. Pus culture showed the growth of C haemolyticum.
Interventions: Broad-spectrum antibiotics, including piperacillin/tazobactam and metronidazole, were administered, and a percutaneous 10-French pigtail catheter for pus drainage and culture was inserted in the liver abscess.
Outcomes: Despite administering intensive treatments, she presented with rapid deterioration in mental status, liver function, and infection markers. She was transferred to the local hospital for palliative conservative treatment.
Lessons: Clostridia infections, including those involving C haemolyticum, are extremely rare, but should be considered as one of the causative organisms of liver abscess formation after TACE because of its rapid and fatal clinical course.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959397 | PMC |
| http://dx.doi.org/10.1097/MD.0000000000010688 | DOI Listing |
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