Acute Chagas disease (ACD) has a distinct epidemiological profile in the Amazon Region, with cases and outbreaks of Trypanosoma cruzi infection being possibly related to the ingestion of contaminated food. Data on ACD in the state of Pará retrieved from 2000 to 2016 from the Brazilian Notifiable Diseases Information System (SINAN) were evaluated. During this period, 2,030 of the 16,807 reported cases were confirmed, with a higher incidence between the months of August and December, thus characterising a seasonal pattern of acute infection, and coinciding with the higher production of "açaí", one fruit likely involved in the oral transmission of the disease. Evaluation of the absolute numbers of confirmed ACD cases secondary to oral infection suggests that infection through this route increased during the 2010-2016 period, differing from what was recorded in terms of vectorial or other infection routes. These findings point to the need of intensifying strategies to prevent or substantially reduce oral transmission.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951676 | PMC |
| http://dx.doi.org/10.1590/0074-02760170298 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Risk Factors for Spotted Fever Group Rickettsioses in Kilimanjaro Region, Tanzania.
Open Forum Infect Dis
December 2024
Centre for International Health, University of Otago, Dunedin, New Zealand.
Article Synopsis
- The study investigated risk factors for spotted fever group rickettsioses (SFGR) in the Kilimanjaro Region, Tanzania, focusing on febrile patients from local hospitals between 2012 and 2014.
- Of 1,190 participants, 54.6% had SFGR exposure, with 9.2% displaying acute SFGR; factors such as age, rural living, and temperature were significant in determining risk.
- The findings highlight that children under 2 years, rural residents, and those in cooler areas may be at higher risk for SFGR, suggesting a need for targeted prevention strategies and additional research on tick exposure.
Challenges in Transitioning from Controlled to Assisted Ventilation in Acute Respiratory Distress Syndrome (ARDS) Management.
J Clin Med
December 2024
Laboratory of Pulmonary Investigation, Carlos Chagas Filho Institute of Biophysics, Centro de Ciências da Saúde, Federal University of Rio de Janeiro, Avenida Carlos Chagas Filho, 373, Bloco G-014, Ilha Do Fundão, Rio de Janeiro 21941-598, RJ, Brazil.
Acute respiratory distress syndrome (ARDS) presents significant challenges in critical care, primarily due to its inflammatory nature, which leads to impaired gas exchange and respiratory mechanics. While mechanical ventilation (MV) is essential for patient support, the transition from controlled to assisted ventilation is complex and may be associated with intensive care unit-acquired weakness, ventilator-induced diaphragmatic dysfunction and patient self-inflicted lung injury. This paper explores the multifaceted challenges encountered during this transition, with a focus on respiratory effort, sedation management, and monitoring techniques, and investigates innovative approaches to enhance patient outcomes.
View Article and Find Full Text PDFUnlocking the power of biomarkers: transforming the diagnosis of acute respiratory distress syndrome.
Expert Rev Mol Diagn
December 2024
Laboratory of Pulmonary Investigation, Carlos Chagas Filho Institute of Biophysics, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Optimizing brain protection after cardiac arrest: advanced strategies and best practices.
Interface Focus
December 2024
Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genova, Italy.
Cardiac arrest (CA) is associated with high incidence and mortality rates. Among patients who survive the acute phase, brain injury stands out as a primary cause of death or disability. Effective intensive care management, including targeted temperature management, seizure treatment and maintenance of normal physiological parameters, plays a crucial role in improving survival and neurological outcomes.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!